Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene

dc.contributor.authorNanamatsu, Azuma
dc.contributor.authorMicanovic, Radmila
dc.contributor.authorKhan, Shehnaz
dc.contributor.authorEl-Achkar, Tarek M.
dc.contributor.authorLaFavers, Kaice A.
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2024-03-22T13:57:23Z
dc.date.available2024-03-22T13:57:23Z
dc.date.issued2023
dc.description.abstract*Serum uromodulin levels are higher in healthy female participants than healthy male participants. *Serum uromodulin levels in participants with normal kidney function do not correlate with eGFR but do correlate with body mass index. *Estrogen increases uromodulin production, likely because of noncanonical and half estrogen response elements in the UMOD gene.
dc.eprint.versionFinal published version
dc.identifier.citationNanamatsu A, Micanovic R, Khan S, El-Achkar TM, LaFavers KA. Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene. Kidney360. 2023;4(9):e1302-e1307. doi:10.34067/KID.0000000000000197
dc.identifier.urihttps://hdl.handle.net/1805/39433
dc.language.isoen_US
dc.publisherWolters Kluwer
dc.relation.isversionof10.34067/KID.0000000000000197
dc.relation.journalKidney360
dc.rightsCC0 1.0 Universalen
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/
dc.sourcePMC
dc.subjectClinical epidemiology
dc.subjectSex difference
dc.subjectGene transcription
dc.titleHealthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene
dc.typeArticle
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