Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene
dc.contributor.author | Nanamatsu, Azuma | |
dc.contributor.author | Micanovic, Radmila | |
dc.contributor.author | Khan, Shehnaz | |
dc.contributor.author | El-Achkar, Tarek M. | |
dc.contributor.author | LaFavers, Kaice A. | |
dc.contributor.department | Medicine, School of Medicine | |
dc.date.accessioned | 2024-03-22T13:57:23Z | |
dc.date.available | 2024-03-22T13:57:23Z | |
dc.date.issued | 2023 | |
dc.description.abstract | *Serum uromodulin levels are higher in healthy female participants than healthy male participants. *Serum uromodulin levels in participants with normal kidney function do not correlate with eGFR but do correlate with body mass index. *Estrogen increases uromodulin production, likely because of noncanonical and half estrogen response elements in the UMOD gene. | |
dc.eprint.version | Final published version | |
dc.identifier.citation | Nanamatsu A, Micanovic R, Khan S, El-Achkar TM, LaFavers KA. Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene. Kidney360. 2023;4(9):e1302-e1307. doi:10.34067/KID.0000000000000197 | |
dc.identifier.uri | https://hdl.handle.net/1805/39433 | |
dc.language.iso | en_US | |
dc.publisher | Wolters Kluwer | |
dc.relation.isversionof | 10.34067/KID.0000000000000197 | |
dc.relation.journal | Kidney360 | |
dc.rights | CC0 1.0 Universal | en |
dc.rights.uri | https://creativecommons.org/publicdomain/zero/1.0 | |
dc.source | PMC | |
dc.subject | Clinical epidemiology | |
dc.subject | Sex difference | |
dc.subject | Gene transcription | |
dc.title | Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene | |
dc.type | Article |