Using human factors methods to mitigate bias in artificial intelligence-based clinical decision support

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2025
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American English
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Oxford University Press
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Abstract

Objectives: To highlight the often overlooked role of user interface (UI) design in mitigating bias in artificial intelligence (AI)-based clinical decision support (CDS).

Materials and methods: This perspective paper discusses the interdependency between AI-based algorithm development and UI design and proposes strategies for increasing the safety and efficacy of CDS.

Results: The role of design in biasing user behavior is well documented in behavioral economics and other disciplines. We offer an example of how UI designs play a role in how bias manifests in our machine learning-based CDS development.

Discussion: Much discussion on bias in AI revolves around data quality and algorithm design; less attention is given to how UI design can exacerbate or mitigate limitations of AI-based applications.

Conclusion: This work highlights important considerations including the role of UI design in reinforcing/mitigating bias, human factors methods for identifying issues before an application is released, and risk communication strategies.

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Cite As
Militello LG, Diiulio J, Wilson DL, et al. Using human factors methods to mitigate bias in artificial intelligence-based clinical decision support. J Am Med Inform Assoc. 2025;32(2):398-403. doi:10.1093/jamia/ocae291
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Journal of the American Medical Informatics Association
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PMC
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Article
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