Potential Dextromethorphan-Induced Serotonin Syndrome Leading to Homicide and Suicide

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dc.contributor.authorPavelka, Matthew M.
dc.contributor.authorKohr, Roland
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2025-02-18T14:18:02Z
dc.date.available2025-02-18T14:18:02Z
dc.date.issued2024-01-30
dc.description.abstractLimited case reports have been published regarding serotonin syndrome due to the combined effects of supratherapeutic levels of dextromethorphan and selective serotonin reuptake inhibitor. We report a case of an adolescent with postmortem findings suggestive of a diagnosis of serotonin syndrome-induced psychosis associated with a double homicide and suicide. Postmortem toxicology of the suicide victim was remarkable for elevated serotonergic metabolites of fluoxetine and dextromethorphan in a 14-year-old male.
dc.eprint.versionFinal published version
dc.identifier.citationPavelka MM, Kohr R. Potential Dextromethorphan-Induced Serotonin Syndrome Leading to Homicide and Suicide. Acad Forensic Pathol. 2024;14(1):21-25. Published 2024 Jan 30. doi:10.1177/19253621231224531
dc.identifier.urihttps://hdl.handle.net/1805/45789
dc.language.isoen_US
dc.publisherSage
dc.relation.isversionof10.1177/19253621231224531
dc.relation.journalAcademic Forensic Pathology
dc.rightsPublisher Policy
dc.sourcePMC
dc.subjectDextromethorphan
dc.subjectFluoxetine
dc.subjectForensic pathology
dc.subjectSerotonin syndrome
dc.titlePotential Dextromethorphan-Induced Serotonin Syndrome Leading to Homicide and Suicide
dc.typeArticle
ul.alternative.fulltexthttps://pmc.ncbi.nlm.nih.gov/articles/PMC10947710/
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