Fragmented QRS Complexes on 12‐Lead ECG: A Marker of Cardiac Sarcoidosis as Detected by Gadolinium Cardiac Magnetic Resonance Imaging
| dc.contributor.author | Homsi, Mohamed | |
| dc.contributor.author | Alsayed, Lamaan | |
| dc.contributor.author | Safadi, Bilal | |
| dc.contributor.author | Mahenthiran, Jo | |
| dc.contributor.author | Das, Mithilesh K. | |
| dc.contributor.department | Medicine, School of Medicine | en_US |
| dc.date.accessioned | 2022-04-19T15:36:08Z | |
| dc.date.available | 2022-04-19T15:36:08Z | |
| dc.date.issued | 2009-10 | |
| dc.description.abstract | Background: Fragmented QRS complexes (fQRS) on a 12‐lead ECG are a marker of myocardial scar in patients with coronary artery disease. Cardiac sarcoidosis is also associated with myocardial granuloma formation and scarring. We evaluated the significance of fQRS on a 12‐lead ECG compared to Gadolinium‐delayed enhancement images (GDE) in cardiac magnetic resonance imaging (CMR). Method and results: The ECGs of patients (n = 17, mean age: 52 ± 11 years, male: 53%) with established diagnosis of sarcoidosis who underwent a CMR for evaluation of cardiac involvement were studied. ECG abnormalities included bundle branch block, Q wave, and fQRS. fQRS, Q wave, and bundle branch block were present in 9 (53%), 1 (6%), and 4 (24%) patients, respectively. The sensitivity and specificity of fQRS for detecting abnormal GDE were 100% and 80%, respectively. Sensitivity and specificity of Q waves were 11% and 100%, respectively. Conclusions: fQRS on a 12‐lead ECG in patients with suspected cardiac sarcoidosis are associated with cardiac involvement as detected by GDE on CMR. | en_US |
| dc.identifier.citation | Homsi M, Alsayed L, Safadi B, Mahenthiran J, Das MK. Fragmented QRS complexes on 12-lead ECG: a marker of cardiac sarcoidosis as detected by gadolinium cardiac magnetic resonance imaging. Ann Noninvasive Electrocardiol. 2009 Oct;14(4):319-26. doi: 10.1111/j.1542-474X.2009.00320.x. PMID: 19804507; PMCID: PMC6932232. | en_US |
| dc.identifier.uri | https://hdl.handle.net/1805/28554 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Wiley | en_US |
| dc.relation.isversionof | 10.1111/j.1542-474X.2009.00320.x | en_US |
| dc.relation.journal | Annals of Noninvasive Electrocardiology | en_US |
| dc.rights | Attribution 4.0 International | * |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | * |
| dc.source | PMC | en_US |
| dc.subject | Sarcoidosis | en_US |
| dc.subject | Cardiac sarcoidosis | en_US |
| dc.subject | Electrocardiography | en_US |
| dc.subject | Magnetic resonance | en_US |
| dc.subject | Gadolinium | en_US |
| dc.subject | Diagnosis | en_US |
| dc.title | Fragmented QRS Complexes on 12‐Lead ECG: A Marker of Cardiac Sarcoidosis as Detected by Gadolinium Cardiac Magnetic Resonance Imaging | en_US |
| dc.type | Article | en_US |