Intensive Cardiac Rehabilitation Outcomes in Patients with Heart Failure

dc.contributor.authorJafri, S. Hammad
dc.contributor.authorGuglin, Maya
dc.contributor.authorRao, Roopa
dc.contributor.authorIlonze, Onyedika
dc.contributor.authorBallut, Kareem
dc.contributor.authorBaloch, Zulfiqar Qutrio
dc.contributor.authorQintar, Mohammed
dc.contributor.authorCohn, Joel
dc.contributor.authorWilcox, Matthew
dc.contributor.authorFreeman, Andrew M.
dc.contributor.authorKalra, Dinesh K.
dc.contributor.authorWu, Wen-Chih
dc.contributor.departmentMedicine, School of Medicine
dc.description.abstractIntroduction: Cardiac rehabilitation (CR) has proven to be beneficial for patients with heart failure (HF), potentially reducing morbidity and mortality while improving fitness and psychological outcomes. Intensive cardiac rehabilitation (ICR) represents an emerging form of CR that has demonstrated advantages for patients with various cardiovascular diseases. Nevertheless, the specific outcomes of ICR in patients with HF remain unknown. Objectives: The purpose of this study is to assess the effectiveness of ICR in patients with HF. Methods: This retrospective study involved 12,950 patients who participated in ICR at 46 centers from January 2016 to December 2020. Patients were categorized into two groups: the HF group, comprising 1400 patients (11%), and the non-HF group, consisting of 11,550 patients (89%). The primary endpoints included the ICR completion rate, changes in body mass index (BMI), exercise minutes per week (EMW), and depression scores (CESD). A t-test was employed to compare variables between the two groups. Results: The HF group comprises older patients, with 37% being females (compared to 44% in the non-HF group). The ICR completion rate was higher in the non-HF group. After ICR completion, adjusted analyses revealed that patients without HF demonstrated a greater improvement in BMI. There were no differences in fitness, as measured via EMW, or in depression scores, as measured via CESD, between the two groups. Conclusions: Despite the lower baseline functional status and psychosocial scores of HF patients compared to non-HF patients, patients with HF were able to attain similar or even better functional and psychosocial outcomes after ICR.
dc.eprint.versionFinal published version
dc.identifier.citationJafri SH, Guglin M, Rao R, et al. Intensive Cardiac Rehabilitation Outcomes in Patients with Heart Failure. J Clin Med. 2023;12(21):6886. Published 2023 Oct 31. doi:10.3390/jcm12216886
dc.relation.journalJournal of Clinical Medicine
dc.rightsAttribution 4.0 Internationalen
dc.subjectHeart failure
dc.subjectGuideline-directed medical therapy
dc.subjectCardiac rehabilitation
dc.subjectIntensive cardiac rehabilitation
dc.subjectWeight loss
dc.titleIntensive Cardiac Rehabilitation Outcomes in Patients with Heart Failure
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