The epidemiology of substance use among street children in resource-constrained settings: a systematic review and meta-analysis

dc.contributor.authorEmbleton, Lonnie
dc.contributor.authorMwangi, Ann
dc.contributor.authorVreeman, Rachel
dc.contributor.authorAyuku, David
dc.contributor.authorBraitstein, Paula
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2025-05-06T07:43:51Z
dc.date.available2025-05-06T07:43:51Z
dc.date.issued2013
dc.description.abstractAims: To compile and analyze critically the literature published on street children and substance use in resource-constrained settings. Methods: We searched the literature systematically and used meta-analytical procedures to synthesize literature that met the review's inclusion criteria. Pooled-prevalence estimates and 95% confidence intervals (CI) were calculated using the random-effects model for life-time substance use by geographical region as well as by type of substance used. Results: Fifty studies from 22 countries were included into the review. Meta-analysis of combined life-time substance use from 27 studies yielded an overall drug use pooled-prevalence estimate of 60% (95% CI = 51-69%). Studies from 14 countries contributed to an overall pooled prevalence for street children's reported inhalant use of 47% (95% CI = 36-58%). This review reveals significant gaps in the literature, including a dearth of data on physical and mental health outcomes, HIV and mortality in association with street children's substance use. Conclusions: Street children from resource-constrained settings reported high life-time substance use. Inhalants are the predominant substances used, followed by tobacco, alcohol and marijuana.
dc.eprint.versionAuthor's manuscript
dc.identifier.citationEmbleton L, Mwangi A, Vreeman R, Ayuku D, Braitstein P. The epidemiology of substance use among street children in resource-constrained settings: a systematic review and meta-analysis. Addiction. 2013;108(10):1722-1733. doi:10.1111/add.12252
dc.identifier.urihttps://hdl.handle.net/1805/47765
dc.language.isoen_US
dc.publisherWiley
dc.relation.isversionof10.1111/add.12252
dc.relation.journalAddiction
dc.rightsPublisher Policy
dc.sourcePMC
dc.subjectHomeless youth
dc.subjectResource-constrained settings
dc.subjectStreet children
dc.subjectSubstance use
dc.subjectSystematic review
dc.subjectVolatile solvent use
dc.titleThe epidemiology of substance use among street children in resource-constrained settings: a systematic review and meta-analysis
dc.typeArticle
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