Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke

dc.contributor.authorMatthews, Caleb R.
dc.contributor.authorHartman, Timothy
dc.contributor.authorMadison, Mackenzie
dc.contributor.authorVillelli, Nicolas W.
dc.contributor.authorNamburi, Niharika
dc.contributor.authorColgate, Cameron L.
dc.contributor.authorFaiza, Zainab
dc.contributor.authorLee, Lawrence S.
dc.contributor.departmentMedicine, School of Medicineen_US
dc.date.accessioned2022-08-16T13:40:13Z
dc.date.available2022-08-16T13:40:13Z
dc.date.issued2021-04-27
dc.description.abstractThe optimal time when surgery can be safely performed after stroke is unknown. The purpose of this study was to investigate how cardiac surgery timing after stroke impacts postoperative outcomes between 2011–2017 were reviewed. Variables were extracted from the institutional Society of Thoracic Surgeons database, statewide patient registry, and medical records. Subjects were classified based upon presence of endocarditis and further grouped by timing of preoperative stroke relative to cardiac surgery: Recent (stroke within two weeks before surgery), Intermediate (between two and six weeks before), and Remote (greater than six weeks before). Postoperative outcomes were compared amongst groups. 157 patients were included: 54 in endocarditis and 103 in non-endocarditis, with 47 in Recent, 26 in Intermediate, and 84 in Remote. 30-day mortality and postoperative stroke rate were similar across the three subgroups for both endocarditis and non-endocarditis. Of patients with postoperative stroke, mortality was 30% (95% CI 4.6–66). Timing of cardiac surgery after stroke occurrence does not seem to affect postoperative stroke or mortality. If postoperative stroke does occur, subsequent stroke-related mortality is high.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationMatthews CR, Hartman T, Madison M, et al. Preoperative stroke before cardiac surgery does not increase risk of postoperative stroke. Sci Rep. 2021;11(1):9025. Published 2021 Apr 27. doi:10.1038/s41598-021-88441-yen_US
dc.identifier.urihttps://hdl.handle.net/1805/29775
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isversionof10.1038/s41598-021-88441-yen_US
dc.relation.journalScientific Reportsen_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.sourcePMCen_US
dc.subjectOutcomes researchen_US
dc.subjectCardiologyen_US
dc.subjectHealth careen_US
dc.subjectMedical researchen_US
dc.subjectRisk factorsen_US
dc.titlePreoperative stroke before cardiac surgery does not increase risk of postoperative strokeen_US
dc.typeArticleen_US
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