Symptomatic central nervous system tuberculoma, a case report in the United States and literature review

dc.contributor.authorMohammadian, Mahsa
dc.contributor.authorButt, Saira
dc.contributor.departmentMedicine, School of Medicineen_US
dc.date.accessioned2019-09-03T18:52:20Z
dc.date.available2019-09-03T18:52:20Z
dc.date.issued2019-06-25
dc.description.abstractIntracranial tuberculoma is one of the rare central nervous system manifestations of Mycobacterium tuberculosis (MTB), seen in only 1% of tuberculosis patients. It can manifest as single or multiple lesions, most commonly located in the frontal and parietal lobes. Clinical features are similar to any space-occupying lesion in the brain and can present in the absence of MTB symptoms in other parts of the body. In this article, a 69-year-old immunocompetent man, with history of treated latent tuberculosis infection (LTBI) was reported. He presented with multiple joint arthralgias, weight loss, odd behavior, forgetfulness, intermittent fevers and syncope. Brain imaging revealed numerous enhancing intra-parenchymal lesions in cerebral and cerebellar hemispheres. Patient was successfully treated with anti-tuberculosis medications and corticosteroids, with clinical improvement on future follow ups. High clinical suspicion for tuberculoma as a differential diagnosis of any brain lesion, even in immunocompetent patients in low MTB prevalence countries, can result in early diagnosis and successful clinical outcomes.en_US
dc.identifier.citationMohammadian, M., & Butt, S. (2019). Symptomatic central nervous system tuberculoma, a case report in the United States and literature review. IDCases, 17, e00582. doi:10.1016/j.idcr.2019.e00582en_US
dc.identifier.urihttps://hdl.handle.net/1805/20757
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.idcr.2019.e00582en_US
dc.relation.journalIDCasesen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/us*
dc.sourcePMCen_US
dc.subjectCentral nervous systemen_US
dc.subjectMycobacterium tuberculosisen_US
dc.subjectTuberculomaen_US
dc.subjectAFB stainen_US
dc.titleSymptomatic central nervous system tuberculoma, a case report in the United States and literature reviewen_US
dc.typeArticleen_US
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