A Rare Case of Esophageal Granular Cell Tumor in Eosinophilic Esophagitis

Abstract

A 25-year-old man with recently diagnosed eosinophilic esophagitis presented for a surveillance esophagogastroduodenoscopy (EGD). He was incidentally found to have a 2-mm submucosal-appearing nodule with a yellow hue in the distal esophagus (Figure A, arrow). The patient denied unintentional weight loss; gastrointestinal symptoms; family history of gastrointestinal malignancy; or tobacco, alcohol, or drug history. Initial biopsies of the lesion showed normal pathology; repeat EGD with stacked biopsies showed granular cell tumor (GCT; Figure B, star) and endoscopic ultrasound showed no deep tumor invasion. The patient was referred for resection and underwent en bloc band-assisted endoscopic mucosal resection (Figures C and D) with pathology confirming GCT without additional abnormalities. Patient is currently asymptomatic and pending surveillance EGD.