Severe Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Coinfection: A Unique Case Series

dc.contributor.authorElhazmi, Alyaa
dc.contributor.authorAl-Tawfiq, Jaffar A.
dc.contributor.authorSallam, Hend
dc.contributor.authorAl-Omari, Awad
dc.contributor.authorAlhumaid, Saad
dc.contributor.authorMady, Ahmad
dc.contributor.authorAl Mutair, Abbas
dc.contributor.departmentMedicine, School of Medicineen_US
dc.date.accessioned2021-04-23T19:46:53Z
dc.date.available2021-04-23T19:46:53Z
dc.date.issued2021
dc.descriptionThis article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.en_US
dc.description.abstractIntroduction The emergence of the Severe Acute Respiratory Syndrome Coroanvirus 2 (SARS-CoV-2) had raised possibilities of coinfection with the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in countries were these two viruses were reported. In this study, we describe the clinical presentation and demographics of eight patients who were coinfected with SARS-CoV-2 and MERS-CoV. Materials and methods This is a case series of hospitalized patients admitted to intensive care units (ICUs). We collected demographics, underlying conditions, presenting symptoms and clinical outcome from the patients’ medical records. Results During the study period from March 14, 2020 to October 19, 2020, there was a total of 67 SARS-CoV-2 ICU admitted patients who underwent simultaneous SARS-CoV-2 and MERS-CoV testing by PCR. Of those patients, 8 (12%) tested positive for both SARS-CoV-2 and MERS-CoV. There were 6 (75%) males, the mean age ± SD was 44.4 ± 11.8 years, and 7 (87.5%) were obese. Of the patients, 7 (87.5%) were non-smokers, 1 (12.5%) had diabetes mellitus, 1 (12.5%) had heart failure, and 1 (12.5%) had been on anti-platelet therapy. The mean hospital length of stay (LOS) was 21.1 ± 11.6 days and the average ICU LOS was 10.9 ± 6.03 days. All patients received supportive therapy and all were treated with corticosteroid. Of all the patients, 4 (50%) were discharged home and 3 (37.5%) died. Conclusion This case series is an important addition to the medical knowledge as it showed the interaction of the coinfection of SARS-CoV-2 and MERS-CoV.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationElhazmi, A., Al-Tawfiq, J. A., Sallam, H., Al-Omari, A., Alhumaid, S., Mady, A., & Al Mutair, A. (2021). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) coinfection: A unique case series. Travel Medicine and Infectious Disease, 41, 102026. https://doi.org/10.1016/j.tmaid.2021.102026en_US
dc.identifier.urihttps://hdl.handle.net/1805/25744
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.tmaid.2021.102026en_US
dc.relation.journalTravel Medicine and Infectious Diseaseen_US
dc.rightsPublic Health Emergencyen_US
dc.sourcePublisheren_US
dc.subjectCOVID-19en_US
dc.subjectSARS-CoV-2en_US
dc.subjectMERS-CoVen_US
dc.titleSevere Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Coinfection: A Unique Case Seriesen_US
dc.typeArticleen_US
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