Characterizing the roles of long non-coding RNA in rat alcohol preference
| dc.contributor.author | Zhou, Ao | |
| dc.contributor.author | Wang, Yadong | |
| dc.contributor.author | Liu, Yunlong | |
| dc.contributor.author | Feng, Weixing | |
| dc.contributor.author | Edenberg, Howard J. | |
| dc.contributor.department | Medical and Molecular Genetics, School of Medicine | en_US |
| dc.date.accessioned | 2017-11-10T18:47:22Z | |
| dc.date.available | 2017-11-10T18:47:22Z | |
| dc.date.issued | 2016-12 | |
| dc.description.abstract | Alcohol is one of the major threats to health in United States. With the emerging of next-generation sequencing technology, the association between alcohol preference and the variants and expression of genes has been investigated. However, the roles of long non-coding RNAs (lncRNA) in alcohol preference remains unclear. In this study, we identified 37 novel lncRNAs that differentially expressed across alcohol preferring (P) and non-preferring (NP) rats. The functional study on these lncRNAs demonstrates that they are associated with gene regulation, as well as neural functions. This suggests that these lncRNAs may contribute to the alcohol preference behaviors. | en_US |
| dc.eprint.version | Author's manuscript | en_US |
| dc.identifier.citation | Zhou, A., Wang, Y., Liu, Y., Feng, W., & Edenberg, H. J. (2016). Characterizing the roles of long non-coding RNA in rat alcohol preference. In 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (pp. 167–173). https://doi.org/10.1109/BIBM.2016.7822513 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1805/14503 | |
| dc.language.iso | en | en_US |
| dc.publisher | IEEE | en_US |
| dc.relation.isversionof | 10.1109/BIBM.2016.7822513 | en_US |
| dc.relation.journal | 2016 IEEE International Conference on Bioinformatics and Biomedicine | en_US |
| dc.rights | Publisher Policy | en_US |
| dc.source | Author | en_US |
| dc.subject | alcohol preference | en_US |
| dc.subject | long non-coding RNA | en_US |
| dc.subject | next generation sequencing | en_US |
| dc.title | Characterizing the roles of long non-coding RNA in rat alcohol preference | en_US |
| dc.type | Article | en_US |