COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

dc.contributor.authorWong, Li Ping
dc.contributor.authorLi Ping, Haridah
dc.contributor.authorDanaee, Mahmoud
dc.contributor.authorAhmed, Jamil
dc.contributor.authorLachyan, Abhishek
dc.contributor.authorCai, Carla Zi
dc.contributor.authorLin, Yulan
dc.contributor.authorHu, Zhijian
dc.contributor.authorTan, Si Ying
dc.contributor.authorLu, Yixiao
dc.contributor.authorCai, Guoxi
dc.contributor.authorNguyen, Di Khanh
dc.contributor.authorSeheli, Farhana Nishat
dc.contributor.authorAlhammadi, Fatma
dc.contributor.authorMadhale, Milkar D.
dc.contributor.authorAtapattu, Muditha
dc.contributor.authorQuazi-Bodhanya, Tasmi
dc.contributor.authorMohajer, Samira
dc.contributor.authorZimet, Gregory D.
dc.contributor.authorZhao, Qinjian
dc.contributor.departmentPediatrics, School of Medicineen_US
dc.description.abstractBACKGROUND: The availability of various types of COVID-19 vaccines and diverse characteristics of the vaccines present a dilemma in vaccination choices, which may result in individuals refusing a particular COVID-19 vaccine offered, hence presenting a threat to immunisation coverage and reaching herd immunity. The study aimed to assess global COVID-19 vaccination intention, vaccine characteristics influencing vaccination acceptance and desirable vaccine characteristics influencing the choice of vaccines. METHODS: An anonymous cross-sectional survey was conducted between 4 January and 5 March 2021 in 17 countries worldwide. Proportions and the corresponding 95% confidence intervals (CI) of COVID-19 vaccine acceptance and vaccine characteristics influencing vaccination acceptance were generated and compared across countries and regions. Multivariable logistic regression analysis was used to determine the factors associated with COVID-19 vaccine hesitancy. RESULTS: Of the 19,714 responses received, 90.4% (95% CI 81.8-95.3) reported likely or extremely likely to receive COVID-19 vaccine. A high proportion of likely or extremely likely to receive the COVID-19 vaccine was reported in Australia (96.4%), China (95.3%) and Norway (95.3%), while a high proportion reported being unlikely or extremely unlikely to receive the vaccine in Japan (34.6%), the U.S. (29.4%) and Iran (27.9%). Males, those with a lower educational level and those of older age expressed a higher level of COVID-19 vaccine hesitancy. Less than two-thirds (59.7%; 95% CI 58.4-61.0) reported only being willing to accept a vaccine with an effectiveness of more than 90%, and 74.5% (95% CI 73.4-75.5) said they would accept a COVID-19 vaccine with minor adverse reactions. A total of 21.0% (95% CI 20.0-22.0) reported not accepting an mRNA vaccine and 51.8% (95% CI 50.3-53.1) reported that they would only accept a COVID-19 vaccine from a specific country-of-origin. Countries from the Southeast Asia region reported the highest proportion of not accepting mRNA technology. The highest proportion from Europe and the Americas would only accept a vaccine produced by certain countries. The foremost important vaccine characteristic influencing vaccine choice is adverse reactions (40.6%; 95% CI 39.3-41.9) of a vaccine and effectiveness threshold (35.1%; 95% CI 33.9-36.4). CONCLUSIONS: The inter-regional and individual country disparities in COVID-19 vaccine hesitancy highlight the importance of designing an efficient plan for the delivery of interventions dynamically tailored to the local population.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationWong, L. P., Li Ping, H., Danaee, M., Ahmed, J., Lachyan, A., Cai, C. Z., Lin, Y., Hu, Z., Tan, S. Y., Lu, Y., Cai, G., Nguyen, D. K., Seheli, F. N., Alhammadi, F., Madhale, M. D., Atapattu, M., Quazi-Bodhanya, T., Mohajer, S., Zimet, G. D., & Zhao, Q. (2021). COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: A global survey of 17 countries. Infectious Diseases of Poverty, 10(1), 122.
dc.relation.journalInfectious Diseases of Povertyen_US
dc.rightsAttribution 4.0 United States
dc.subjectSocioeconomic Factorsen_US
dc.subjectSurveys and Questionnairesen_US
dc.subjectCOVID-19 vaccineen_US
dc.subjectYoung Adulten_US
dc.titleCOVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countriesen_US
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