Brief report: Endothelial colony-forming cells and inflammatory monocytes in HIV
dc.contributor.author | Hays, Travis R. | |
dc.contributor.author | Mund, Julie A. | |
dc.contributor.author | Liu, Ziyue | |
dc.contributor.author | Case, Jamie | |
dc.contributor.author | Ingram, David A. | |
dc.contributor.author | Gupta, Samir K. | |
dc.contributor.department | Department of Medicine, IU School of Medicine | en_US |
dc.date.accessioned | 2016-08-12T18:42:58Z | |
dc.date.available | 2016-08-12T18:42:58Z | |
dc.date.issued | 2015-04-15 | |
dc.description.abstract | The relationships between HIV infection, monocyte activation, and endothelial colony-forming cells (ECFCs) are unknown. We compared ECFC, intermediate monocytes (CD14 CD16), and nonclassical monocytes (CD14 CD16) levels in HIV-infected participants virologically suppressed on antiretroviral therapy, HIV-infected treatment-naive participants, and HIV-uninfected healthy controls. ECFC levels were significantly higher in the HIV-infected virologically suppressed group compared with the uninfected controls. CD14 CD16 percentages (but not CD14 CD16 cells) were significantly higher in both HIV-infected groups vs. uninfected controls. In the HIV-infected groups, ECFCs and CD14 CD16 intermediate monocytes were significantly and inversely correlated. Lower availability of ECFCs may partly explain the relationship between greater intermediate monocytes and atherosclerosis in HIV. | en_US |
dc.eprint.version | Author's manuscript | en_US |
dc.identifier.citation | Hays, T. R., Mund, J. A., Liu, Z., Case, J., Ingram, D. A., & Gupta, S. K. (2015). Endothelial Colony Forming Cells and Inflammatory Monocytes in HIV. Journal of Acquired Immune Deficiency Syndromes (1999), 68(5), 550–553. http://doi.org/10.1097/QAI.0000000000000506 | en_US |
dc.identifier.issn | 1944-7884 | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/10689 | |
dc.language.iso | en_US | en_US |
dc.publisher | Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins | en_US |
dc.relation.isversionof | 10.1097/QAI.0000000000000506 | en_US |
dc.relation.journal | Journal of Acquired Immune Deficiency Syndromes (1999) | en_US |
dc.rights | Publisher Policy | en_US |
dc.source | PMC | en_US |
dc.subject | Endothelial Progenitor Cells | en_US |
dc.subject | physiology | en_US |
dc.subject | HIV Infections | en_US |
dc.subject | immunology | en_US |
dc.subject | pathology | en_US |
dc.subject | Monocytes | en_US |
dc.title | Brief report: Endothelial colony-forming cells and inflammatory monocytes in HIV | en_US |
dc.type | Article | en_US |