Acute Cryptococcal Immune Reconstitution Inflammatory Syndrome in a Patient on Natalizumab
Date
2016-01
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English
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Oxford
Abstract
Presented is the first case of acute immune reconstitution inflammatory syndrome (IRIS)-associated cryptococcal meningoencephalitis in a patient on natalizumab for multiple sclerosis. The patient developed acute cerebral edema after initiation of amphotericin B. We propose several mechanisms that explain the acuity of IRIS in this specific patient population and suggest possible therapies.
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Gundacker, N. D., Jordan, S. J., Jones, B. A., Drwiega, J. C., & Pappas, P. G. (2016, January). Acute Cryptococcal Immune Reconstitution Inflammatory Syndrome in a Patient on Natalizumab. In Open forum infectious diseases (Vol. 3, No. 1, p. ofw038). Oxford University Press. https://doi.org/10.1093/ofid/ofw038
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Open Forum Infectious Diseases
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Final published version