MAGGIC, STS, and EuroSCORE II Risk Score Comparison After Aortic and Mitral Valve Surgery

dc.contributor.authorZhuo, David X.
dc.contributor.authorBilchick, Kenneth C.
dc.contributor.authorShah, Kajal P.
dc.contributor.authorMehta, Nishaki K.
dc.contributor.authorMwansa, Hunter
dc.contributor.authorNkanza-Kabaso, Kanasa
dc.contributor.authorKwon, Younghoon
dc.contributor.authorBreathett, Khadijah K.
dc.contributor.authorHilton-Buchholz, Ebony J.
dc.contributor.authorMazimba, Sula
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2025-01-21T13:00:25Z
dc.date.available2025-01-21T13:00:25Z
dc.date.issued2021
dc.description.abstractObjectives: To compare the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) risk score with the established Society of Thoracic Surgeons (STS) and EuroSCORE II risk prediction models regarding mortality discrimination after aortic and mitral valve surgery. Design: Retrospective cohort study. Setting: Single tertiary academic medical center. Participants: A total of 259 patients who underwent open aortic valve replacement or open mitral valve repair/replacement from 2009-2014. Interventions: Retrospective chart review. Measurements and main results: MAGGIC, STS, and EuroSCORE II risk scores for each patient were studied using binary logistic regression and receiver operating characteristic analysis for the primary endpoint of one-year mortality and secondary endpoint of 30-day mortality. One-year mortality C-statistics were similar across risk scores (STS 0.709, 95% confidence interval [CI] 0.578-0.841; MAGGIC 0.673, 95% CI 0.547-0.799; EuroSCORE II 0.642, 95% CI 0.521-0.762; p = 0.56 between STS and MAGGIC; p = 0.20 between STS and EuroSCORE II; and p = 0.69 between MAGGIC and EuroSCORE II). Thirty-day mortality C-statistics also were similar between STS (0.797, 95% CI 0.655-0.939; p < 0.0001 v null hypothesis), MAGGIC (0.721, 95% CI 0.581-0.860; p = 0.33 v STS), and EuroSCORE II (0.688, 95% CI 0.557-0.818; p = 0.06 v STS; p = 0.68 v MAGGIC). Conclusions: The MAGGIC risk score performs similarly to STS and EuroSCORE II risk models in mortality discrimination after aortic and mitral valve surgery, albeit in a small sample size. This finding has important implications in establishing MAGGIC as a viable prognostic model in this population subset, with fewer variables and ease of use representing key advantages over STS and EuroSCORE II.
dc.eprint.versionAuthor's manuscript
dc.identifier.citationZhuo DX, Bilchick KC, Shah KP, et al. MAGGIC, STS, and EuroSCORE II Risk Score Comparison After Aortic and Mitral Valve Surgery. J Cardiothorac Vasc Anesth. 2021;35(6):1806-1812. doi:10.1053/j.jvca.2020.11.053
dc.identifier.urihttps://hdl.handle.net/1805/45318
dc.language.isoen_US
dc.publisherElsevier
dc.relation.isversionof10.1053/j.jvca.2020.11.053
dc.relation.journalJournal of Cardiothoracic and Vascular Anesthesia
dc.rightsPublisher Policy
dc.sourcePMC
dc.subjectAortic valve replacement
dc.subjectMitral valve repair/replacement
dc.subjectMortality
dc.subjectPerioperative risk assessment
dc.subjectValvular heart surgery
dc.titleMAGGIC, STS, and EuroSCORE II Risk Score Comparison After Aortic and Mitral Valve Surgery
dc.typeArticle
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