Blood-based biomarkers for Alzheimer's disease and related dementias: Keys to success and things to consider

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dc.contributor.authorZetterberg, Henrik
dc.contributor.authorApostolova, Liana G.
dc.contributor.authorSnyder, Peter J.
dc.contributor.departmentRadiology and Imaging Sciences, School of Medicineen_US
dc.date.accessioned2020-01-03T17:21:03Z
dc.date.available2020-01-03T17:21:03Z
dc.date.issued2019-11-14
dc.description.abstractDuring the last two decades, considerable progress has been made in the field of fluid and imaging biomarkers for neurodegenerative dementias. As a result, the most recent research and clinical guidelines (the National Institute on Aging and Alzheimer's Association, International Working Group 2, National Institute for Health and Care Excellence) incorporate cerebrospinal fluid (CSF) and positron emission tomography (PET) biomarkers in the diagnostic criteria of dementia and mild cognitive impairment due to Alzheimer's disease (AD) [[1], [2], [3]]. However, as both CSF and amyloid PET examinations require expert knowledge and are of limited availability outside specialized memory clinics, there is no doubt that blood tests would be much easier to implement in clinical medicine and as screening tools when recruiting patients for clinical trials.en_US
dc.identifier.citationZetterberg, H., Apostolova, L. G., & Snyder, P. J. (2019). Blood-based biomarkers for Alzheimer's disease and related dementias: Keys to success and things to consider. Alzheimer's & dementia (Amsterdam, Netherlands), 11, 784–786. doi:10.1016/j.dadm.2019.10.001en_US
dc.identifier.urihttps://hdl.handle.net/1805/21714
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.dadm.2019.10.001en_US
dc.relation.journalAlzheimer's & Dementiaen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourcePMCen_US
dc.subjectFluid biomarkersen_US
dc.subjectImaging biomarkersen_US
dc.subjectNeurodegenerative dementiasen_US
dc.subjectCerebrospinal fluid (CSF)en_US
dc.subjectPositron emission tomography (PET)en_US
dc.titleBlood-based biomarkers for Alzheimer's disease and related dementias: Keys to success and things to consideren_US
dc.typeArticleen_US
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