A Possible Etiology of the Infertile 46XX Male Subject
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Date
1983-07
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American English
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Elsevier
Abstract
We report on an infertile male patient with the predominant 46XX female karyotype. A testicular biopsy revealed widely separated testicular tubules, absence of sperm formation and large numbers of Leydig cells. Chromosome studies, including measurements of the X chromosomes, showed a significant difference between the lengths of the short arm of the 2 X chromosomes. This information lends support for an X-Y chromosome interchange as the etiology of this syndrome. The clinical features of this rare syndrome and other theories of etiology of XX male subjects are discussed.
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Butler, M. G., Walzak, M. P., Sanger, W. G., & Todd, C. T. (1983). A Possible Etiology Of The Infertile 46XX Male Subject. The Journal of Urology, 130(1), 154–156.
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The Journal of Urology
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PMC
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Article
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