Exhaustive Suzuki-Miyaura Reactions of Polyhalogenated Heteroarenes with Alkyl Boronic Pinacol Esters

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2017-06-29
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American English
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Royal Society of Chemistry
Abstract

A novel Suzuki-Miyaura protocol is described that enables the exhaustive alkylation of polychlorinated pyridines. This method facilitates a formal synthesis of normuscopyridine and the rapid assembly of a dumbbell shaped portion of a [2]rotaxane.

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Laulhé, S., Blackburn, J. M., & Roizen, J. L. (2017). Exhaustive Suzuki-Miyaura reactions of polyhalogenated heteroarenes with alkyl boronic pinacol esters. Chemical communications (Cambridge, England), 53(53), 7270-7273.
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Chemical communications (Cambridge, England)
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PMC
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