Generation of Casp8FL122/123GG Mice Using CRISPR-Cas9 Technology

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dc.contributor.authorPelletier, Stephane
dc.contributor.authorTummers, Bart
dc.contributor.authorGreen, Douglas R.
dc.contributor.departmentMedical and Molecular Genetics, School of Medicineen_US
dc.date.accessioned2022-04-22T15:32:59Z
dc.date.available2022-04-22T15:32:59Z
dc.date.issued2020-12-18
dc.description.abstractThe purpose of this protocol is to describe the generation of missense mutations in mice using CRISPR-Cas9 technology. The current protocol focuses on the generation of a Casp8 FL122/123GG missense mutation, but it can be adapted to introduce any missense or nonsense mutation. For complete details on the use and execution of this protocol, please refer to Tummers et al. (2020).en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationPelletier, S., Tummers, B., & Green, D. R. (2020). Generation of Casp8FL122/123GG mice using CRISPR-Cas9 technology. STAR protocols, 1(3), 100181. doi:10.1016/j.xpro.2020.100181en_US
dc.identifier.urihttps://hdl.handle.net/1805/28700
dc.language.isoen_USen_US
dc.publisherCell Pressen_US
dc.relation.isversionof10.1016/j.xpro.2020.100181en_US
dc.relation.journalSTAR Protocolsen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourcePMCen_US
dc.subjectCRISPRen_US
dc.subjectModel Organismsen_US
dc.titleGeneration of Casp8FL122/123GG Mice Using CRISPR-Cas9 Technologyen_US
dc.typeArticleen_US
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