MicroRNAs on the move: microRNAs in astrocyte-derived ApoE particles regulate neuronal function

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Karahan2021Micro-PubPol.pdf (1.04 MB)
Date
2021
Authors
Karahan, Hande
Dabin, Luke C.
Tate, Mason D.
Kim, Jungsu
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American English
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Medical and Molecular Genetics, School of Medicine
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Elsevier
Abstract

In this issue of Neuron, Li et al. (2021) demonstrate that ApoE lipoprotein particles shuttle miRNAs from astrocytes to neurons, leading to inhibition of cholesterol biosynthesis and an increase in histone acetylation in neurons.

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Acetylation, Apolipoproteins E, Astrocytes, Cholesterol, MicroRNAs, Neurons
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Karahan H, Dabin LC, Tate MD, Kim J. MicroRNAs on the move: microRNAs in astrocyte-derived ApoE particles regulate neuronal function. Neuron. 2021;109(6):907-909. doi:10.1016/j.neuron.2021.02.021
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Neuron
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https://hdl.handle.net/1805/42720
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https://doi.org/10.1016/j.neuron.2021.02.021
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Final published version
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