Performance of TEM-PCR vs Culture for Bacterial Identification in Pediatric Musculoskeletal Infections

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dc.contributor.authorWood, James B.
dc.contributor.authorSesler, Cheryl
dc.contributor.authorStalons, Donald
dc.contributor.authorGrigorenko, Elena
dc.contributor.authorSchoenecker, Jonathan G.
dc.contributor.authorCreech, C. Buddy
dc.contributor.authorThomsen, Isaac P.
dc.contributor.departmentPediatrics, School of Medicineen_US
dc.date.accessioned2019-05-15T13:45:19Z
dc.date.available2019-05-15T13:45:19Z
dc.date.issued2018-05-22
dc.description.abstractImproved diagnostics are needed for children with musculoskeletal infections (MSKIs). We assessed the performance of target-enriched multiplex polymerase chain reaction (TEM-PCR) in children with MSKI. TEM-PCR was concordant with culture in pathogen identification and antibiotic susceptibility testing, while increasing the overall yield of pathogen detection. This technology has the potential to inform judicious antimicrobial use early in the disease course.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationWood, J. B., Sesler, C., Stalons, D., Grigorenko, E., Schoenecker, J. G., Creech, C. B., & Thomsen, I. P. (2018). Performance of TEM-PCR vs Culture for Bacterial Identification in Pediatric Musculoskeletal Infections. Open forum infectious diseases, 5(6), ofy119. doi:10.1093/ofid/ofy119en_US
dc.identifier.urihttps://hdl.handle.net/1805/19293
dc.language.isoen_USen_US
dc.publisherOxford Academicen_US
dc.relation.isversionof10.1093/ofid/ofy119en_US
dc.relation.journalOpen Forum Infectious Diseasesen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.sourcePMCen_US
dc.subjectDiagnosticsen_US
dc.subjectMusculoskeletal infectionsen_US
dc.subjectOsteomyelitisen_US
dc.subjectPediatricsen_US
dc.subjectSeptic arthritisen_US
dc.titlePerformance of TEM-PCR vs Culture for Bacterial Identification in Pediatric Musculoskeletal Infectionsen_US
dc.typeArticleen_US
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