Systems biology of platelet-vessel wall interactions
| dc.contributor.author | Chen, Yolande | |
| dc.contributor.author | Corey, Seth Joel | |
| dc.contributor.author | Kim, Oleg V. | |
| dc.contributor.author | Alber, Mark S. | |
| dc.contributor.department | Department of Medicine, IU School of Medicine | en_US |
| dc.date.accessioned | 2017-07-19T19:04:38Z | |
| dc.date.available | 2017-07-19T19:04:38Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | Platelets are small, anucleated cells that participate in primary hemostasis by forming a hemostatic plug at the site of a blood vessel's breach, preventing blood loss. However, hemostatic events can lead to excessive thrombosis, resulting in life-threatening strokes, emboli, or infarction. Development of multi-scale models coupling processes at several scales and running predictive model simulations on powerful computer clusters can help interdisciplinary groups of researchers to suggest and test new patient-specific treatment strategies. | en_US |
| dc.eprint.version | Author's manuscript | en_US |
| dc.identifier.citation | Chen, Y., Corey, S. J., Kim, O. V., & Alber, M. S. (2014). Systems Biology of Platelet–Vessel Wall Interactions. Advances in Experimental Medicine and Biology, 844, 85–98. http://doi.org/10.1007/978-1-4939-2095-2_5 | en_US |
| dc.identifier.uri | https://hdl.handle.net/1805/13513 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Springer | en_US |
| dc.relation.isversionof | 10.1007/978-1-4939-2095-2_5 | en_US |
| dc.relation.journal | Advances in Experimental Medicine and Biology | en_US |
| dc.rights | Publisher Policy | en_US |
| dc.source | PMC | en_US |
| dc.subject | Platelets | en_US |
| dc.subject | Blood vessels | en_US |
| dc.subject | Hemostasis | en_US |
| dc.subject | Thrombosis | en_US |
| dc.title | Systems biology of platelet-vessel wall interactions | en_US |
| dc.type | Article | en_US |