Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop

dc.contributor.authorLeopold, Jane A.
dc.contributor.authorKawut, Steven M.
dc.contributor.authorAldred, Micheala A.
dc.contributor.authorArcher, Stephen L.
dc.contributor.authorBenza, Ray L.
dc.contributor.authorBristow, Michael R.
dc.contributor.authorBrittain, Evan L.
dc.contributor.authorChesler, Naomi
dc.contributor.authorDeMan, Frances S.
dc.contributor.authorErzurum, Serpil C.
dc.contributor.authorGladwin, Mark T.
dc.contributor.authorHassoun, Paul M.
dc.contributor.authorHemnes, Anna R.
dc.contributor.authorLahm, Tim
dc.contributor.authorLima, Joao A. C.
dc.contributor.authorLoscalzo, Joseph
dc.contributor.authorMaron, Bradley A.
dc.contributor.authorMercer Rosa, Laura
dc.contributor.authorNewman, John H.
dc.contributor.authorRedline, Susan
dc.contributor.authorRich, Stuart
dc.contributor.authorRischard, Franz
dc.contributor.authorSugeng, Lissa
dc.contributor.authorTang, W. H. Wilson
dc.contributor.authorTedford, Ryan J.
dc.contributor.authorTsai, Emily J.
dc.contributor.authorVentetuolo, Corey E.
dc.contributor.authorZhou, YouYang
dc.contributor.authorAggarwal, Neil R.
dc.contributor.authorXiao, Lei
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2024-04-01T09:11:13Z
dc.date.available2024-04-01T09:11:13Z
dc.date.issued2021
dc.description.abstractRight ventricular dysfunction is a hallmark of advanced pulmonary vascular, lung parenchymal, and left heart disease, yet the underlying mechanisms that govern (mal)adaptation remain incompletely characterized. Owing to the knowledge gaps in our understanding of the right ventricle (RV) in health and disease, the National Heart, Lung, and Blood Institute (NHLBI) commissioned a working group to identify current challenges in the field. These included a need to define and standardize normal RV structure and function in populations; access to RV tissue for research purposes and the development of complex experimental platforms that recapitulate the in vivo environment; and the advancement of imaging and invasive methodologies to study the RV within basic, translational, and clinical research programs. Specific recommendations were provided, including a call to incorporate precision medicine and innovations in prognosis, diagnosis, and novel RV therapeutics for patients with pulmonary vascular disease.
dc.eprint.versionAuthor's manuscript
dc.identifier.citationLeopold JA, Kawut SM, Aldred MA, et al. Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop [published correction appears in Circ Heart Fail. 2021 Aug;14(8):e000069]. Circ Heart Fail. 2021;14(6):e007975. doi:10.1161/CIRCHEARTFAILURE.120.007975
dc.identifier.urihttps://hdl.handle.net/1805/39629
dc.language.isoen_US
dc.publisherAmerican Heart Association
dc.relation.isversionof10.1161/CIRCHEARTFAILURE.120.007975
dc.relation.journalCirculation: Heart Failure
dc.rightsPublisher Policy
dc.sourcePMC
dc.subjectHeart failure
dc.subjectPulmonary hypertension
dc.subjectRight ventricular function
dc.titleDiagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop
dc.typeArticle
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