Development of an Artificial Finger-Like Knee Loading Device to Promote Bone Health

dc.contributor.authorKorupolu, Sandeep
dc.contributor.authorChien, Stanley
dc.contributor.authorYokota, Hiroki
dc.contributor.authorAnwar, Sohel
dc.contributor.departmentMechanical and Energy Engineering, School of Engineering and Technologyen_US
dc.date.accessioned2019-06-28T17:45:21Z
dc.date.available2019-06-28T17:45:21Z
dc.date.issued2017-11
dc.description.abstractThis study presents the development of an innovative artificial finger-like device that provides position specific mechanical loads at the end of the long bone and induces mechanotransduction in bone. Bone cells such as osteoblasts are the mechanosensitive cells that regulate bone remodelling. When they receive gentle, periodic mechanical loads, new bone formation is promoted. The proposed device is an under-actuated multi-fingered artificial hand with 4 fingers, each having two phalanges. These fingers are connected by mechanical linkages and operated by a worm gearing mechanism. With the help of 3D printing technology, a prototype device was built mostly using plastic materials. The experimental validation results show that the device is capable of generating necessary forces at the desired frequencies, which are suitable for the stimulation of bone cells and the promotion of bone formation. It is recommended that the device be tested in a clinical study for confirming its safety and efficacy with patients.en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationKorupolu, S., Chien, S., Yokota, H., & Anwar, S. (2017). Development of an Artificial Finger-Like Knee Loading Device to Promote Bone Health. Journal of biomedical science and engineering, 10(11), 550–561. doi:10.4236/jbise.2017.1011041en_US
dc.identifier.urihttps://hdl.handle.net/1805/19759
dc.language.isoen_USen_US
dc.publisherScientific Research Publishingen_US
dc.relation.isversionof10.4236/jbise.2017.1011041en_US
dc.relation.journalJournal of Biomedical Science and Engineeringen_US
dc.rightsPublisher Policyen_US
dc.sourcePMCen_US
dc.subjectArtificial Handen_US
dc.subjectBone Growthen_US
dc.subjectMechanical Loadingen_US
dc.subjectOsteoblastsen_US
dc.titleDevelopment of an Artificial Finger-Like Knee Loading Device to Promote Bone Healthen_US
dc.typeArticleen_US
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