Complement System in Lung Disease

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2014-10
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American English
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American Thoracic Society
Abstract

In addition to its established contribution to innate immunity, recent studies have suggested novel roles for the complement system in the development of various lung diseases. Several studies have demonstrated that complement may serve as a key link between innate and adaptive immunity in a variety of pulmonary conditions. However, the specific contributions of complement to lung diseases based on innate and adaptive immunity are just beginning to emerge. Elucidating the role of complement-mediated immune regulation in these diseases will help to identify new targets for therapeutic interventions.

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Pandya, P. H., & Wilkes, D. S. (2014). Complement System in Lung Disease. American Journal of Respiratory Cell and Molecular Biology, 51(4), 467–473. http://doi.org/10.1165/rcmb.2013-0485TR
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American Journal of Respiratory Cell and Molecular Biology
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PMC
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This item is under embargo {{howLong}}