New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop

Simple item page
dc.contributor.authorTelpoukhovskaia, Maria A.
dc.contributor.authorMurdy, Thomas J.
dc.contributor.authorMarola, Olivia J.
dc.contributor.authorCharland, Kevin
dc.contributor.authorMacLean, Michael
dc.contributor.authorLuquez, Tain
dc.contributor.authorLish, Alexandra M.
dc.contributor.authorNeuner, Sarah
dc.contributor.authorDunn, Amy
dc.contributor.authorOnos, Kristen D.
dc.contributor.authorWiley, Jesse
dc.contributor.authorArcher, Derek
dc.contributor.authorHuentelman, Matthew J.
dc.contributor.authorArnold, Matthias
dc.contributor.authorMenon, Vilas
dc.contributor.authorGoate, Alison
dc.contributor.authorVan Eldik, Linda J.
dc.contributor.authorTerrito, Paul R.
dc.contributor.authorHowell, Gareth R.
dc.contributor.authorCarter, Gregory W.
dc.contributor.authorO’Connell, Kristen M. S.
dc.contributor.authorKaczorowski, Catherine C.
dc.contributor.author2022 JAX CADR Workshop
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2024-06-27T08:17:44Z
dc.date.available2024-06-27T08:17:44Z
dc.date.issued2024-03-10
dc.description.abstractIntroduction: In September 2022, The Jackson Laboratory Center for Alzheimer's and Dementia Research (JAX CADR) hosted a workshop with leading researchers in the Alzheimer's disease and related dementias (ADRD) field. Methods: During the workshop, the participants brainstormed new directions to overcome current barriers to providing patients with effective ADRD therapeutics. The participants outlined specific areas of focus. Following the workshop, each group used standard literature search methods to provide background for each topic. Results: The team of invited experts identified four key areas that can be collectively addressed to make a significant impact in the field: (1) Prioritize the diversification of disease targets, (2) enhance factors promoting resilience, (3) de-risk clinical pipeline, and (4) centralize data management. Discussion: In this report, we review these four objectives and propose innovations to expedite ADRD therapeutic pipelines.
dc.eprint.versionFinal published version
dc.identifier.citationTelpoukhovskaia MA, Murdy TJ, Marola OJ, et al. New directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop. Alzheimers Dement (N Y). 2024;10(1):e12458. Published 2024 Mar 10. doi:10.1002/trc2.12458
dc.identifier.urihttps://hdl.handle.net/1805/41938
dc.language.isoen_US
dc.publisherWiley
dc.relation.isversionof10.1002/trc2.12458
dc.relation.journalAlzheimer’s & Dementia: Translational Research & Clinical Interventions
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourcePMC
dc.subjectAlzheimer's disease and related dementias (ADRD)
dc.subjectADRD therapeutics
dc.subjectJackson Laboratory Center for Alzheimer's and Dementia Research (JAX CADR)
dc.titleNew directions for Alzheimer's disease research from the Jackson Laboratory Center for Alzheimer's and Dementia Research 2022 workshop
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Telpoukhovskaia2024New-CCBYNCND.pdf
Size:
2.96 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.04 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Open Access Policy Articles
Department of Medicine Works