Anti-integrin therapy for retinovascular diseases

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Date
2020
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English
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Taylor & Francis
Abstract

Integrins are a family of multi-functional cell-adhesion molecules, heterodimeric receptors that connect extracellular matrix (ECM) to actin cytoskeleton in the cell cortex, thus regulating cellular adhesion, migration, proliferation, invasion, survival, and apoptosis. Consequently, integrins play a role in inflammation, angiogenesis and fibrosis.

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Bhatwadekar, A. D., Kansara, V., Luo, Q., & Ciulla, T. (2020). Anti-integrin therapy for retinovascular diseases. Expert Opinion on Investigational Drugs, 29(9), 935–945. https://doi.org/10.1080/13543784.2020.1795639
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Expert Opinion on Investigational Drugs
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