High-definition colonoscopy versus Endocuff versus EndoRings versus Full-Spectrum Endoscopy for adenoma detection at colonoscopy: a multicenter randomized trial
dc.contributor.author | Rex, Douglas K. | |
dc.contributor.author | Repici, Alessandro | |
dc.contributor.author | Gross, Seth A. | |
dc.contributor.author | Hassan, Cesare | |
dc.contributor.author | Ponugoti, Prasanna L. | |
dc.contributor.author | Garcia, Jonathan R. | |
dc.contributor.author | Broadley, Heather M. | |
dc.contributor.author | Thygesen, Jack C. | |
dc.contributor.author | Sullivan, Andrew W. | |
dc.contributor.author | Tippins, William W. | |
dc.contributor.author | Main, Samuel A. | |
dc.contributor.author | Eckert, George J. | |
dc.contributor.author | Vemulapalli, Krishna C. | |
dc.contributor.department | Medicine, School of Medicine | en_US |
dc.date.accessioned | 2018-04-19T15:16:08Z | |
dc.date.available | 2018-04-19T15:16:08Z | |
dc.date.issued | 2018 | |
dc.description.abstract | Background Devices used to improve polyp detection during colonoscopy have seldom been compared with each other. Methods We performed a 3-center prospective randomized trial comparing high-definition (HD) forward-viewing colonoscopy alone to HD with Endocuff to HD with EndoRings to the Full Spectrum Endoscopy (FUSE) system. Patients were age ≥50 years and had routine indications and intact colons. The study colonoscopists were all proven high-level detectors. The primary endpoint was adenomas per colonoscopy (APC) Results Among 1,188 patients who completed the study, APC with Endocuff (APC Mean ± SD 1.82 ± 2.58), EndoRings (1.55 ± 2.42), and standard HD colonoscopy (1.53 ± 2.33) were all higher than FUSE (1.30 ± 1.96,) (p<0.001 for APC). Endocuff was higher than standard HD colonoscopy for APC (p=0.014) . Mean cecal insertion times with FUSE (468 ± 311 seconds) and EndoRings (403 ± 263 seconds) were both longer than with Endocuff (354 ± 216 seconds) (p=0.006 and 0.018, respectively). Conclusions For high-level detectors at colonoscopy, forward-viewing HD instruments dominate the FUSE system, indicating that for these examiners image resolution trumps angle of view. Further, Endocuff is a dominant strategy over EndoRings and no mucosal exposure device on a forward-viewing HD colonoscope. | en_US |
dc.eprint.version | Author's manuscript | en_US |
dc.identifier.citation | Rex, D. K., Repici, A., Gross, S. A., Hassan, C., Ponugoti, P. L., Garcia, J. R., … Vemulapalli, K. C. (2018). High-definition colonoscopy versus Endocuff versus EndoRings versus Full-Spectrum Endoscopy for adenoma detection at colonoscopy: a multicenter randomized trial. Gastrointestinal Endoscopy. https://doi.org/10.1016/j.gie.2018.02.043 | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/15872 | |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.isversionof | 10.1016/j.gie.2018.02.043 | en_US |
dc.relation.journal | Gastrointestinal Endoscopy | en_US |
dc.rights | Publisher Policy | en_US |
dc.source | Author | en_US |
dc.subject | hd colonoscopy | en_US |
dc.subject | adenoma detection | en_US |
dc.subject | full spectrum endoscopy | en_US |
dc.title | High-definition colonoscopy versus Endocuff versus EndoRings versus Full-Spectrum Endoscopy for adenoma detection at colonoscopy: a multicenter randomized trial | en_US |
dc.type | Article | en_US |