Enhancing predicted fluoride varnish efficacy and post-treatment compliance by means of calcium-containing gummy bears
dc.contributor.author | Lippert, Frank | |
dc.contributor.author | Al Dehailan, Laila | |
dc.contributor.author | Castiblanco, Gina A. | |
dc.contributor.author | Tagelsir, Azza | |
dc.contributor.author | Buckley, Christine | |
dc.contributor.author | Eckert, George J. | |
dc.contributor.department | Cariology, Operative Dentistry and Dental Public Health, School of Dentistry | en_US |
dc.date.accessioned | 2018-04-20T18:24:32Z | |
dc.date.available | 2018-04-20T18:24:32Z | |
dc.date.issued | 2018 | |
dc.description.abstract | Objectives This study determined whether consumption of calcium-containing gummies prior to fluoride varnish application enhances plaque fluoride retention and compliance with post-varnish application instructions. Methods The present study followed a multi-center, parallel, randomized, and laboratory analyst-blind design. Following IRB approval, parent consent and child assent, 44 subjects (7–12 years), were randomized to either gummy or no-gummy study groups. A baseline plaque sample was obtained after a wash-out period. Fluoride varnish (5% NaF) was applied; subjects in the gummy group received two calcium-containing gummies prior to varnish application. Subjects were given two questionnaires to complete (subject and parent) to investigate adherence to post-treatment instructions. Three days later, a second plaque sample was obtained. Plaque was analyzed for plaque fluid and solid fluoride concentrations. Fluoride data were analyzed using Wilcoxon Rank Sum tests, questionnaire data using Pearson chi-square tests. Results Plaque fluid fluoride did not change pre- to post-treatment in the gummy group (mean ± sd: 8.8 ± 5.7 μmol/l vs. 10.0 ± 6.3 μmol/l; p = 0.265) or in the no-gummy group (8.1 ± 4.4 μmol/l vs. 16.1 ± 20.0 μmol/l; p = 0.058). Groups were not different for plaque fluid fluoride pre-treatment (p = 1.000), post-treatment (p = 0.904), or change (p = 0.904). Plaque solid fluoride did not change pre- to post-treatment in the gummy group (0.89 ± 1.10 μmol/g vs. 1.37 ± 1.77 μmol/g; p = 0.073) or in the no-gummy group (0.68 ± 0.77 μmol/g vs. 2.01 ± 5.00 μmol/g; p = 0.190). Groups were not different for plaque solid fluoride pre-treatment (p = 1.000), post-treatment (p = 0.466), or change (p = 0.874). No significant differences were found between groups for questionnaire responses. Conclusion This study failed to demonstrate an effect of calcium-containing gummies in enhancing plaque fluoride retention. | en_US |
dc.eprint.version | Author's manuscript | en_US |
dc.identifier.citation | Lippert, F., Al Dehailan, L., Castiblanco, G. A., Tagelsir, A. A., Buckley, C., & Eckert, G. J. (2018). Enhancing predicted fluoride varnish efficacy and post-treatment compliance by means of calcium-containing gummy bears. Journal of Dentistry. https://doi.org/10.1016/j.jdent.2018.03.015 | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/15890 | |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.relation.isversionof | 10.1016/j.jdent.2018.03.015 | en_US |
dc.relation.journal | Journal of Dentistry | en_US |
dc.rights | Publisher Policy | en_US |
dc.source | Author | en_US |
dc.subject | fluoride varnish | en_US |
dc.subject | plaque | en_US |
dc.subject | caries | en_US |
dc.title | Enhancing predicted fluoride varnish efficacy and post-treatment compliance by means of calcium-containing gummy bears | en_US |
dc.type | Article | en_US |