Targeting fibroblast growth factor receptor (FGFR) pathway in renal cell carcinoma

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dc.contributor.authorMassari, Francesco
dc.contributor.authorCiccarese, Chiara
dc.contributor.authorSantoni, Matteo
dc.contributor.authorLopez-Beltran, Antonio
dc.contributor.authorScarpelli, Marina
dc.contributor.authorMontironi, Rodolfo
dc.contributor.authorCheng, Liang
dc.contributor.departmentDepartment of Pathology and Laboratory Medicine, IU School of Medicineen_US
dc.date.accessioned2016-05-26T18:30:24Z
dc.date.available2016-05-26T18:30:24Z
dc.date.issued2015
dc.description.abstractFibroblast growth factor receptor (FGFR) pathway is involved in driving vascular endothelial growth factor (VEGF)-independent tumor angiogenesis, as a compensatory mechanism to escape VEGF-targeted therapies. Therefore, targeting FGF/FGFR axis seems to be a promising strategy in order to inhibit tumor angiogenesis and reduce resistance to VEGF receptor-tyrosine kinase inhibitors. This editorial is focused on the role of FGF/FGFR pathway in renal cell carcinoma and on the ongoing trials of emerging agents targeting this axis.en_US
dc.eprint.versionAuthor's manuscripten_US
dc.identifier.citationMassari, F., Ciccarese, C., Santoni, M., Lopez-Beltran, A., Scarpelli, M., Montironi, R., & Cheng, L. (2015). Targeting fibroblast growth factor receptor (FGFR) pathway in renal cell carcinoma. Expert Review of Anticancer Therapy, 15(12), 1367–1369. http://doi.org/10.1586/14737140.2015.1110488en_US
dc.identifier.urihttps://hdl.handle.net/1805/9679
dc.language.isoenen_US
dc.publisherTaylor and Francisen_US
dc.relation.isversionof10.1586/14737140.2015.1110488en_US
dc.relation.journalExpert Review of Anticancer Therapyen_US
dc.rightsPublisher Policyen_US
dc.sourceAuthoren_US
dc.subjectfibroblast growth factor receptoren_US
dc.subjectkidneyen_US
dc.subjectpersonalized medicineen_US
dc.titleTargeting fibroblast growth factor receptor (FGFR) pathway in renal cell carcinomaen_US
dc.typeArticleen_US
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