Estrogen receptor involvement in the response of human keratinocytes to ultraviolet B irradiation
dc.contributor.advisor | Spandau, Dan F. | |
dc.contributor.author | Farrington, Daphne L. | |
dc.contributor.other | Harrington, Maureen A. | |
dc.contributor.other | Nakshatri, Harikrishna | |
dc.date.accessioned | 2015-04-23T18:36:55Z | |
dc.date.available | 2015-04-23T18:36:55Z | |
dc.date.issued | 2014 | |
dc.degree.date | 2014 | en_US |
dc.degree.discipline | Department of Biochemistry & Molecular Biology | en |
dc.degree.grantor | Indiana University | en_US |
dc.degree.level | M.S. | en_US |
dc.description.abstract | The signaling mechanisms involved in UVB-induced skin cancer are complex and although the scope of this work is inherently limited in focus, the findings may provide insight into how estrogen receptor signaling impacts cell growth, senescence, and apoptosis to protect keratinocytes. Additional signaling due to E2-activation of the estrogen receptor may provide back-up or redundant pathways in response to UVB. | en_US |
dc.identifier.uri | https://hdl.handle.net/1805/6241 | |
dc.identifier.uri | http://dx.doi.org/10.7912/C2/1874 | |
dc.language.iso | en_US | en_US |
dc.subject | UVB | en_US |
dc.subject | Estrogen receptor | en_US |
dc.subject | Keratinocytes | en_US |
dc.subject.lcsh | Skin -- Cancer | en_US |
dc.subject.lcsh | Ultraviolet radiation | en_US |
dc.subject.lcsh | Solar radiation | en_US |
dc.subject.lcsh | Estrogen -- Receptors | en_US |
dc.subject.lcsh | Selective estrogen receptor modulators | en_US |
dc.subject.lcsh | Cells -- Growth | en_US |
dc.subject.lcsh | Cells -- Aging | en_US |
dc.subject.lcsh | Cells -- Death | en_US |
dc.subject.lcsh | Apoptosis | en_US |
dc.subject.lcsh | Keratinocytes | en_US |
dc.title | Estrogen receptor involvement in the response of human keratinocytes to ultraviolet B irradiation | en_US |
dc.type | Thesis | en |
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