The Changing Face of Hypophosphatemic Disorders in the FGF-23 Era

dc.contributor.authorLee, Janet Y.
dc.contributor.authorImel, Erik A.
dc.contributor.departmentMedicine, School of Medicine
dc.date.accessioned2025-05-05T16:18:05Z
dc.date.available2025-05-05T16:18:05Z
dc.date.issued2013
dc.description.abstractIn the past decade, research in genetic disorders of hypophosphatemia has significantly expanded our understanding of phosphate metabolism. X-linked hypophosphatemia (XLH) is the most common inherited form of rickets due to renal phosphate wasting. Recent understanding of the mechanisms of disease and role of fibroblast growth factor 23 (FGF-23) in XLH and other hypophosphatemic disorders have opened new potential therapeutic avenues. We will discuss the current standard of treatment for XLH as well as promising future directions under study.
dc.eprint.versionAuthor's manuscript
dc.identifier.citationLee JY, Imel EA. The changing face of hypophosphatemic disorders in the FGF-23 era. Pediatr Endocrinol Rev. 2013;10 Suppl 2(0 2):367-379.
dc.identifier.urihttps://hdl.handle.net/1805/47735
dc.language.isoen_US
dc.publisherY.S. Medical Media
dc.relation.journalPediatric Endocrinology Reviews
dc.rightsPublisher Policy
dc.sourcePMC
dc.subjectFamilial hypophosphatemic rickets
dc.subjectFibroblast growth factors
dc.subjectPhosphates
dc.titleThe Changing Face of Hypophosphatemic Disorders in the FGF-23 Era
dc.typeArticle
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