Browsing by Subject "resilience"
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Item Assessing the Impact of COVID-19 on Social Work Students: Burnout and Resilience During a Global Pandemic(IU School of Social Work, 2023-03-22) Keesler, John M.; Wilkerson, David; White, Kurt; Dickinson, Stephanie; School of Social WorkCOVID-19 had a profound impact on teaching and learning at academic institutions across the globe. This study examined the experiences of social work students (n = 884) during the pandemic and their associated level of burnout. Using a mixed methods approach, data from an online survey within a school of social work at a large Midwestern university were examined using stepwise regression and thematic analysis. Student demographics, academic characteristics, and experiences with COVID-19 were examined as predictors of burnout. Resilience was tested as a moderator of the association between COVID-19 experiences and burnout. Regression models accounted for 34.3% to 45.5% of variance across three domains of burnout (i.e., exhaustion, cynicism, and professional/academic efficacy), with COVID-related experiences accounting for most of the variance. Although resilience had a significant main effect, the interactions of resilience and COVID-19 experiences were not significant. Quantitative results were illuminated by thematic analysis of the qualitative data from which emerged four major themes: online teaching pedagogy, impact of COVID-19, transition of teaching and learning, and affective domains of learning. Engaging in humanistic education is discussed as a possible approach to circumvent burnout, bolster student resilience, and encourage academic success.Item Family resistance as a tool in urban school reform(Teachers College Press, 2014-08) Santamaría Graff, CristinaItem Finding My Way: Using Visual Journals to Forge a Path of Resilience and Resistance(Penn State Libraries Open Publishing, 2023-09-06) Kulinski, Alexa R.; Herron School of Art and DesignOver the last four years of my K-12 visual arts teaching career, I faithfully kept visual journals, filling them with stories of my experiences in the classroom. What initially began as an experiment as I searched for a tool to help me navigate new challenges within a public school system, eventually led me to realize that my visual journals were a valuable resource to better understand myself as a teacher, my place within the system, and a resource for resilience. In this article, I use narrative and arts-based approaches to explore the ways I leveraged visual journals as a tool for resilience by integrating humor, fostering a sense of accomplishment and self-efficacy, as well as retaking ownership of my journey to fight back. Through sharing this narrative I hope to illustrate some of the ways visual journals can help arts educators find resilience and strength to resist during challenging times.Item Gene-based GWAS and -biological pathway analysis of the resilience of executive functioning(Springer US, 2014-03) Mukherjee, Shubhabrata; Kim, Sungeun; Ramanan, Vijay K.; Gibbons, Laura E.; Nho, Kwangsik; Glymour, M. Maria; Ertekin-Taner, Nilüfer; Montine, Thomas J.; Saykin, Andrew J.; Crane, Paul K.; Alzheimer’s Disease Neuroimaging Initiative; Department of Radiology and Imaging Sciences, School of MedicineResilience in executive functioning (EF) is characterized by high EF measured by neuropsychological test performance despite structural brain damage from neurodegenerative conditions. We previously reported single nucleotide polymorphism (SNP) genome-wide association study (GWAS) results for EF resilience. Here, we report gene- and pathway-based analyses of the same resilience phenotype, using an optimal SNP-set (Sequence) Kernel Association Test (SKAT) for gene-based analyses (conservative threshold for genome-wide significance = 0.05/18,123=2.8×10−6) and the gene-set enrichment package GSA-SNP for biological pathway analyses (False discovery rate (FDR) < 0.05). Gene-based analyses found a genome-wide significant association between RNASE13 and EF resilience (p=1.33×10−7). Genetic pathways involved with dendritic/neuron spine, presynaptic membrane, postsynaptic density etc. were enriched with association to EF resilience. Although replication of these results is necessary, our findings indicate the potential value of gene- and pathway-based analyses in research on determinants of cognitive resilience.Item Genetic variants and functional pathways associated with resilience to Alzheimer’s disease(Oxford, 2020-08-25) Dumitrescu, Logan; Mahoney, Emily R; Mukherjee, Shubhabrata; Lee, Michael L; Bush, William S; Engelman, Corinne D; Lu, Qiongshi; Fardo, David W; Trittschuh, Emily H; Mez, Jesse; Kaczorowski, Catherine; Hernandez Saucedo, Hector; Widaman, Keith F; Buckley, Rachel; Properzi, Michael; Mormino, Elizabeth; Yang, Hyun-Sik; Harrison, Tessa; Hedden, Trey; Nho, Kwangsik; Andrews, Shea J; Tommet, Doug; Hadad, Niran; Sanders, R Elizabeth; Ruderfer, Douglas M; Gifford, Katherine A; Moore, Annah M; Cambronero, Francis; Zhong, Xiaoyuan; Raghavan, Neha S.; Vardarajan, Badri; Pericak-Vance, Margaret A.; Farrer, Lindsay A.; Wang, Li-San; Cruchaga, Carlos; Schellenberg, Gerard; Cox, Nancy J.; Haines, Jonathan L,; Keene, C. Dirk; Saykin, Andrew J.; Larson, Eric B.; Sperling, Reisa A.; Mayeux, Richard; Bennett, David A.; Schneider, Julie A.; Crane, Paul K.; Jefferson, Angela L.; Hohman, Timothy J.; Radiology and Imaging Sciences, School of MedicineApproximately 30% of older adults exhibit the neuropathological features of Alzheimer’s disease without signs of cognitive impairment. Yet, little is known about the genetic factors that allow these potentially resilient individuals to remain cognitively unimpaired in the face of substantial neuropathology. We performed a large, genome-wide association study (GWAS) of two previously validated metrics of cognitive resilience quantified using a latent variable modelling approach and representing better-than-predicted cognitive performance for a given level of neuropathology. Data were harmonized across 5108 participants from a clinical trial of Alzheimer’s disease and three longitudinal cohort studies of cognitive ageing. All analyses were run across all participants and repeated restricting the sample to individuals with unimpaired cognition to identify variants at the earliest stages of disease. As expected, all resilience metrics were genetically correlated with cognitive performance and education attainment traits (P-values < 2.5 × 10−20), and we observed novel correlations with neuropsychiatric conditions (P-values < 7.9 × 10−4). Notably, neither resilience metric was genetically correlated with clinical Alzheimer’s disease (P-values > 0.42) nor associated with APOE (P-values > 0.13). In single variant analyses, we observed a genome-wide significant locus among participants with unimpaired cognition on chromosome 18 upstream of ATP8B1 (index single nucleotide polymorphism rs2571244, minor allele frequency = 0.08, P = 2.3 × 10−8). The top variant at this locus (rs2571244) was significantly associated with methylation in prefrontal cortex tissue at multiple CpG sites, including one just upstream of ATPB81 (cg19596477; P = 2 × 10−13). Overall, this comprehensive genetic analysis of resilience implicates a putative role of vascular risk, metabolism, and mental health in protection from the cognitive consequences of neuropathology, while also providing evidence for a novel resilience gene along the bile acid metabolism pathway. Furthermore, the genetic architecture of resilience appears to be distinct from that of clinical Alzheimer’s disease, suggesting that a shift in focus to molecular contributors to resilience may identify novel pathways for therapeutic targets.Item The Impact of a Resilience-Building Intervention with Indianapolis Latino Teenagers(Office of the Vice Chancellor for Research, 2015-04-17) Gonzalez, Manuela Roa; Bigatti, Silvia M.; Conrad, KatrinaBackground and Objectives: Data shows that Indiana Latino high school students face a 65 percent higher rate of suicide attempts and a 24 percent higher rate of depression than their non-Hispanic white peers. Together with the help of the Latino Health Organization, a team of researchers performed a pilot study to investigate this and from the findings developed a one-year resilience-building intervention called Your Life. Your Story. This program aims to increase self-mastery and resilience, as well as decrease rates of depression. This is accomplished through evidence-based, interdisciplinary components such as art, physical activity, and a resilience-building curriculum. In the summer of 2014, 30 Latino teens, ages 12 to 17, became the first to participate in the Your Life. Your Story pilot program. Methods: To evaluate the effectiveness of the program on increasing resilience and decreasing depression at the program’s six-month mark, participants completed surveys. The Kutcher Adolescent Depression Scale (KADS) was utilized to measure depression, and the Resilience, Attitudes, and Skills Profile (RASP) was utilized to measure resilience. Paired samples t-tests were utilized to measure changes over time, from the data collected prior to the program start. Results: At the program’s six-month mark, depression levels (M=4.16, SD=4.018) continue to have decreased significantly, t(17)=2.270, p=0.037, and a significant increase in resilience (M=114.88, SD=14), has also been sustained, t(22)=-2.221, p=0.037. Conclusions: Results suggest that the Your Life. Your Story. Program is creating a significant impact on the Latino teen participants in regards to depression and resilience levels. More data will be collected at the end of the program (June 2016) and will be analyzed to evaluate the overall impact of the program.Item The Influence of Social Isolation and Other Risk Factors on Older African Immigrants' Emotional Well-Being(2022-08) Adeniji, Dolapo Omolola; Adamek, Margaret; Hong, Michin; Gentle-Genitty, Carolyn; Huber, LesaSocial isolation has been documented as a significant challenge for older adults, including those who are immigrants. The conventional wisdom blames social isolation among older immigrant adults on language barriers, living arrangements, and age at migration, however, this does not allow for analytical clarity on how social isolation interacts with other important risk factors to influence emotional well-being among older African immigrants. This study offers an important contribution to the existing knowledge by examining how social isolation and other risk factors interact to impact emotional well-being among older African immigrants. It uses life course theory, acculturation theory, resilience theory, and cumulative risk theory to identify the relevant stressors or risk factors such as living arrangements, financial satisfaction, acculturation predictors, transportation, and grandchild care. A mixed-methods approach integrating quantitative and qualitative research methods was used in the study. For the collection of quantitative data, 163 participants aged 60 and over completed an online or mailed survey. Hierarchical regression was used to analyze the quantitative data. Findings showed that ethnic social relations and living arrangements had a unique contribution to the social isolation of the participants. Also, social isolation, ethnic social relations, and financial satisfaction significantly influenced the emotional well-being of study participants. For the study’s qualitative data, the researcher conducted in-depth interviews with 11 participants, age 63-79, by telephone. Five major themes were generated from the data using a thematic analysis approach, which included (a) minimal social engagement outside of the home, (b) barriers to social engagement, (c) satisfaction with finances, (d) fewer socialization consequences, and (e) coping strategies. The overall finding showed that the participants lacked social engagement outside of the home, which negatively affected their emotional well-being. Implications for social work practice and policy as well as recommendations were emphasized in the study.Item Local capacity and resilience to flooding: community responsiveness to the community ratings system program incentives(Springer, 2015-09) Sadiq, Abdul-Akeem; Noonan, Douglas S.; School of Public and Environmental AffairsTo incentivize more community flood risks mitigation, the US Congress implemented the community rating system (CRS) in 1990. The CRS seeks to help communities build capacity to address flood risks and become more resilient to future flood disasters. Communities participating in CRS can reduce their flood risks and enjoy discounted premiums (up to 45 %) on federally required flood insurance commensurate with their community’s CRS score. A participant community is placed into one of the ten classes depending on its CRS score. Although previous research finds that the program’s structure creates opportunities for communities participating in CRS to respond to its incentives, no study has examined the characteristics of communities that changed their mitigation behavior due to this incentive scheme. In order to evaluate the performance of CRS and its tiered incentive structure, this study investigates the extent to which communities are responding strategically to CRS incentives and the characteristics of those communities behaving strategically. This study uses a regression discontinuity approach to compare the characteristics of communities above and below CRS class thresholds. The results show strategic behavior of communities participating in CRS. Communities with more information-based flood management activities, lower property values, lower flood risk, and lower population densities are more likely to respond strategically with respect to smaller CRS subsidies. For larger subsidies, the results indicate that CRS communities with higher property values are more likely to respond strategically to the policy incentives. The study concludes with a discussion of the implications of these results for the CRS program.Item Micro-RNA profiles of pathology and resilience in posterior cingulate cortex of cognitively intact elders(Oxford University Press, 2024-03-07) Kelley, Christy M.; Maloney, Bryan; Beck, John S.; Ginsberg, Stephen D.; Liang, Winnie; Lahiri, Debomoy K.; Mufson, Elliott J.; Counts, Scott E.; Psychiatry, School of MedicineThe posterior cingulate cortex (PCC) is a key hub of the default mode network underlying autobiographical memory retrieval, which falters early in the progression of Alzheimer’s disease (AD). We recently performed RNA sequencing of post-mortem PCC tissue samples from 26 elderly Rush Religious Orders Study participants who came to autopsy with an ante-mortem diagnosis of no cognitive impairment but who collectively displayed a range of Braak I–IV neurofibrillary tangle stages. Notably, cognitively unimpaired subjects displaying high Braak stages may represent cognitive resilience to AD pathology. Transcriptomic data revealed elevated synaptic and ATP-related gene expression in Braak Stages III/IV compared with Stages I/II, suggesting these pathways may be related to PCC resilience. We also mined expression profiles for small non-coding micro-RNAs (miRNAs), which regulate mRNA stability and may represent an underexplored potential mechanism of resilience through the fine-tuning of gene expression within complex cellular networks. Twelve miRNAs were identified as differentially expressed between Braak Stages I/II and III/IV. However, the extent to which the levels of all identified miRNAs were associated with subject demographics, neuropsychological test performance and/or neuropathological diagnostic criteria within this cohort was not explored. Here, we report that a total of 667 miRNAs are significantly associated (rho > 0.38, P < 0.05) with subject variables. There were significant positive correlations between miRNA expression levels and age, perceptual orientation and perceptual speed. By contrast, higher miRNA levels correlated negatively with semantic and episodic memory. Higher expression of 15 miRNAs associated with lower Braak Stages I–II and 47 miRNAs were associated with higher Braak Stages III–IV, suggesting additional mechanistic influences of PCC miRNA expression with resilience. Pathway analysis showed enrichment for miRNAs operating in pathways related to lysine degradation and fatty acid synthesis and metabolism. Finally, we demonstrated that the 12 resilience-related miRNAs differentially expressed in Braak Stages I/II versus Braak Stages III/IV were predicted to regulate mRNAs related to amyloid processing, tau and inflammation. In summary, we demonstrate a dynamic state wherein differential PCC miRNA levels are associated with cognitive performance and post-mortem neuropathological AD diagnostic criteria in cognitively intact elders. We posit these relationships may inform miRNA transcriptional alterations within the PCC relevant to potential early protective (resilience) or pathogenic (pre-clinical or prodromal) responses to disease pathogenesis and thus may be therapeutic targets.Item Psychiatric Rehabilitation Journal in the Era of COVID-19(APA, 2020) Resnick, Sandra G.; Roe, David; Salyers, Michelle P.; Psychology, School of ScienceThe global health crisis caused by the coronavirus pandemic (COVID-19) has brought about previously unimaginable changes to all of health care, including the field of psychiatric rehabilitation. Given these dramatic changes, we pose this editorial to contemplate our mission and how we can best serve the field. We raise questions about how psychiatric rehabilitation will evolve and restate our steadfast commitment to publishing impactful research that shapes the field. We also remain hopeful, knowing psychiatric rehabilitation practitioners, researchers, and participants are pragmatic, persistent, and resilient, and will find opportunities for creativity and innovation even during this difficult time.