Browsing by Subject "Zoledronic Acid"

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    Skeletal accumulation of fluorescently-tagged zoledronate is higher in animals with early stage chronic kidney disease
    (Springer, 2018-09-01) Swallow, Elizabeth A.; Aref, Mohammad W.; Chen, Neal; Byiringo, Innocent; Hammond, Max A.; McCarthy, Brian P.; Territo, Paul R.; Kamocka, Malgorzata M.; Winfree, Seth; Dunn, Kenneth W.; Moe, Sharon M.; Allen, Matthew R.; Anatomy and Cell Biology, School of Medicine
    This work examines the skeletal accumulation of fluorescently-tagged zoledronate in an animal model of chronic kidney disease. The results show higher accumulation 24-hours post-dose in animals with lower kidney function due to greater amounts of binding at individual surfaces.