Browsing by Subject "Micrometastatic Disease"

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    Anti-VEGF therapy as adjuvant therapy: clouds on the horizon?
    (BioMed Central, 2009-05-18) Schneider, Bryan P.; Sledge Jr, George W.; Medicine, School of Medicine
    Anti-angiogenic therapies have demonstrated their value in the setting of advanced cancer, and are being explored for use in micrometastatic disease. Recent preclinical studies suggest that adjuvant anti-vascular endothelial growth factor (VEGF) therapies may increase the risk of metastasis. How concerning are these preclinical studies, and should they affect our willingness to explore anti-VEGF therapy in the adjuvant setting?