Anti-VEGF therapy as adjuvant therapy: clouds on the horizon?

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Date
2009-05-18
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American English
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BioMed Central
Abstract

Anti-angiogenic therapies have demonstrated their value in the setting of advanced cancer, and are being explored for use in micrometastatic disease. Recent preclinical studies suggest that adjuvant anti-vascular endothelial growth factor (VEGF) therapies may increase the risk of metastasis. How concerning are these preclinical studies, and should they affect our willingness to explore anti-VEGF therapy in the adjuvant setting?

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Schneider, B.P., Sledge, G.W. Anti-VEGF therapy as adjuvant therapy: clouds on the horizon?. Breast Cancer Res 11, 303 (2009). https://doi.org/10.1186/bcr2250
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Breast Cancer Research
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