Browsing by Subject "Data Curation"

Now showing 1 - 4 of 4
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    Data Curation Competencies, Skill sets, and Tools Analysis
    (Springer, 2024) Murillo, Angela P.; Yoon, Angela; Duncan, Mitch; Thomas-Fennelly, Adam
    The project aims to extend the current understanding of data curation competencies by examining existing skill sets and tools through a systematic analysis of data curation literature. For this research, the researchers reviewed forty-two data curation-related documents, including peer-reviewed literature, conference papers, and book sections through descriptive quantitative analysis and inductive qualitative content analysis based on a systematically created document protocol to extract informational items about the documents, as well as competencies, skills, and tools relevant to data curation activities. This paper presents the preliminary findings of this analysis and future steps for this project.
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    Text mining for drug-drug interaction
    (Springer-Verlag, 2014) Wu, Heng-Yi; Chiang, Chien-Wei; Li, Lang; Department of Medicine, IU School of Medicine
    In order to understand the mechanisms of drug-drug interaction (DDI), the study of pharmacokinetics (PK), pharmacodynamics (PD), and pharmacogenetics (PG) data are significant. In recent years, drug PK parameters, drug interaction parameters, and PG data have been unevenly collected in different databases and published extensively in literature. Also the lack of an appropriate PK ontology and a well-annotated PK corpus, which provide the background knowledge and the criteria of determining DDI, respectively, lead to the difficulty of developing DDI text mining tools for PK data collection from the literature and data integration from multiple databases.To conquer the issues, we constructed a comprehensive pharmacokinetics ontology. It includes all aspects of in vitro pharmacokinetics experiments, in vivo pharmacokinetics studies, as well as drug metabolism and transportation enzymes. Using our pharmacokinetics ontology, a PK corpus was constructed to present four classes of pharmacokinetics abstracts: in vivo pharmacokinetics studies, in vivo pharmacogenetic studies, in vivo drug interaction studies, and in vitro drug interaction studies. A novel hierarchical three-level annotation scheme was proposed and implemented to tag key terms, drug interaction sentences, and drug interaction pairs. The utility of the pharmacokinetics ontology was demonstrated by annotating three pharmacokinetics studies; and the utility of the PK corpus was demonstrated by a drug interaction extraction text mining analysis.The pharmacokinetics ontology annotates both in vitro pharmacokinetics experiments and in vivo pharmacokinetics studies. The PK corpus is a highly valuable resource for the text mining of pharmacokinetics parameters and drug interactions.
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    Thematic Trends in Data Curation Literature
    (Wiley, 2024) Murillo, Angela P.; Yoon , Ayong
    The field of data curation is rapidly changing due to new developments in technologies and techniques for conducting data work. As the field of data curation evolves, researchers, practitioners, and educators need to be able to respond to these developments. One way to understand trends in a field is by examining published literature. This study first gathered data curation literature through a modified systematic literature review with the framing question, ‘What competencies, skill sets, and proficiencies are needed to conduct data curation activities?’. These literatures were then analyzed using bibliometric analysis, visual analysis of the citation data, and topic modeling to understand trends in the data curation field.
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    Trends in Data Curation: Competencies and Tools
    (Wiley, 2024) Murillo, Angela P.; Yoon , Ayoung
    Library and information science has led data curation research and education for the last two decades, providing data curation education, professional development programs, and a robust professional opportunity. To keep current with the latest trends in competencies and tools needed to conduct data curation activities, this research conducted a systematic literature review of literature that captures competencies and tools to build a framework of current trends in data curation work that educators can utilize to ensure up-to-date educational materials for the next generation of data curation professionals. This poster presents the preliminary findings of this data curation competencies and tools analysis.