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Item The association between deciduous dentin sclerosis and calcium hydroxide methyl cellulose base material(1958) Klein, Arthur Irving, 1922-Seventy five children in the early mixed dentition stage with operative dentistry completed on 351 deciduous teeth were observed from 4 to 28 months with periodic bitewing radiographs taken at intervals of from 4 to 10 months. These cases contained 191 deciduous teeth in which a calcium hydroxide methyl cellulose base material was placed beneath the alloy restorations (test teeth) and 160 deciduous teeth in which no base material was utilized beneath the alloy restorations (control teeth). In each instance all carious dentin was removed before the base material or restoration was completed. A visual densitometric evaluation utilizing sclerotic index which is an estimation of the occurrence and intensity of dentin sclerosis by inspection of bitewing radiographs. This evaluation indicates that 93% of the test teeth gave evidence of dentin sclerosis beneath the area of calcium hydroxide base material while 99% of the control teeth showed no radiographic evidence of dentin sclerosis. An instrumental densitometric evaluation was made of the projected bitewing x-ray film images of 115 deciduous teeth utilizing the Elwood Densitometer. The results of this evaluation indicate a localized increase of dentin sclerosis, or dentin calcification. Ranging from 0% to 125% in the test teeth, immediately beneath the calcium hydroxide base material. The control teeth showed an increased dentin density range of from 0% to 20% immediately beneath the alloy restoration. Histologic examination, both ground and deca1cified sections, Were made of 20 deciduous teeth with and without calcium hydroxide ethyl cellulose base material beneath their alloy restorations. The sections indicated that the sclerotic areas seen radiographically beneath the calcium hydroxide base material cannot be correlated with the histologic picture. Microscopically this shows a markedly irregular secondary dentin characterized by a definite diminution of dentinal tubules, with an increased amount of dentin matrix. These changes could have taken place as a result of age, caries or cavity preparation. From the results of this research it is apparent that a calcium hydroxide methyl cellulose base material is effective in the production of sclerotic dentin in deciduous teeth. There is no doubt that the “white area” seen radiographically is an area of sclerosis of the existing dentin and not an area of recalcification of carious dentin.Item The effect of formocresol and calcium hydroxide on the dental pulps of rhesus monkeys(1963) Spedding, Robert H., 1931-Item Evaluation of a new pulp capping agent: a clinical investigation(1979) Nirschl, Ronald Francis; Poland, Charles, III; Koerber, Leonard G.; Barton, Paul; Starkey, Paul E.This study compared clinical results of two calcium hydroxide bases used in indirect pulp therapy on human teeth. Thirty-four teeth with deep carious lesions were treated with indirect pulp therapy. Eighteen teeth were treated with commercially available Improved Dycal and 16 teeth were treated with an experimental calcium hydroxide formula. Evaluation was made at intervals of three and six months. After three months, periapical and bitewing radiographs were made and the teeth were examined clinically for signs of pulpal degeneration. At the six-month evaluation, in addition to the radiographic and clinical examinations, cavities were re-entered and the unsound residual dentin was removed to ascertain the presence of a so1id dentinal base. Removal of all unsound residual dentin without an exposure of the pulp, as well as the clinical and radiographic examinations, were used to determine clinically successful treatment. In the experimental group 15 teeth were successfully treated; a success rate of 94.4 percent. Seventeen teeth in the control group demonstrated successful indirect pulp therapy; a success rate of 93.75 percent.Item Evaluation of contact angle between root canal sealers and dentin treated with calcium hydroxide and irrigation solutions(2018) Nakaparksin, Pranai; Platt, Jeffrey; Levon , John A.; Bringas, Josef S.; Brown, David T.Background: Numerous studies have reported the effect of long-term use of calcium hydroxide Ca(OH)2 to dentin. Nevertheless, there is little information available about the effect of Ca(OH)2 on wettability to the dentin. Objective: To investigate the effect of Ca(OH)2 application on dentin for two and four weeks on the wettability of two root canal sealers. Methods: Polished caries-free human dentin discs (n = 156) were allocated into 12 groups; G1 and G3 had two weeks’ treatment, G4 and G6, four weeks treatment. G1 and 101 G4 were treated with sterile water. G2, G3, G5 and G6 were treated with Ca(OH)2. G1, G3, G4, and G6 were irrigated with 6.0-percent NaOCl and 17-percent EDTA while G2, and G5 were irrigated with sterile water. Then, contact angles between Tubli-Seal and the treated dentin surfaces were measured. G7 and G12 were treated in the same fashion but were treated with BC sealer. Surface morphology evaluation of G1 and G6 was carried out by scanning electron microscopy (SEM) and energy-dispersive x-ray spectroscopy (EDX). Statistics were performed using three-way ANOVA and pair-wise comparisons between groups (α = 0.05). Results: Tubli-Seal (G1 through G6) had significantly smaller values for contact angles than BC sealer (G7 through G12) (p < 0.05). For the Tubli-Seal groups (G1 through G6), G4 had the highest mean of contact angles at 104.9 ± 1.9°, whereas G5 presented the lowest mean of contact angles at 85.4 ± 15.1. For the BC sealer groups (G7 through G12), G10 had the highest mean of contact angles at 145.4 ± 1.3°, while G11 demonstrated the lowest mean of contact angles at 130.2 ± 2.6°. Groups with Ca(OH)2 treatment with water irrigation (G2, 5, 11) had significantly lower contact angle than groups with Ca(OH)2 with chemical irrigation (G3, 6, 12) (p < 0.05), except G8, 9. According to SEM and EDX, water irrigation solution showed higher remaining Ca(OH)2 than irrigation with the chemical solution while Ca(OH)2 with chemical irrigation 102 demonstrated no Ca(OH)2 remaining after irrigation, similar to the surface of the control group. Conclusion: Within the limitations of this study, Tubli-seal has better wettability on dentin than BC sealer. Remaining calcium hydroxide demonstrated a trend toward decreased contact angle between dentin and root canal sealers. Moreover, two-minute irrigation with 6-percent NaOCl and 17-percent EDTA can remove calcium hydroxide from polished dentin surfaces.Item Indiana State Board of Health. Monthly Bulletin, 1907 Vol. 9 No. 11(11/1/1907) Barnard, H. E.Item Indiana State Board of Health. Monthly Bulletin, 1907 Vol. 9 No. 5(5/1/1907) Barnard, H. E.Item Indiana State Board of Health. Monthly Bulletin, 1907 Vol. 9 No. 7(7/1/1907) Barnard, H. E.Item Pulp vitality of primary molars with deep caries treated with ART restorations: 2-year RCT(Pediatric Dentistry, 2022) da Silva, Gabriela Seabra; Raggio, Daniela Prócida; Mello-Moura, Anna Carolina Volpi; Gimenez, Thais; Montagner, Anelise Fernandes; Floriano, Isabela; Lara, Juan Sebastian; Calvo, Ana Flávia Bissoto; Pascareli-Carlos, Aline Maquiné; Tedesco, Tamara Kerber; Cariology, Operative Dentistry and Dental Public Health, School of DentistryThe aim of this study was to compare the pulp vitality of primary teeth with deep caries treated with two restorative techniques. The restoration survival rate was also evaluated as a secondary outcome. Children aged from 4 to 8 years with at least one deep carious lesion in molars were selected at the Ibirapuera University dental clinic. One hundred and eight deciduous molars were allocated into two groups: (1) restoration with calcium hydroxide cement lining followed by filling with high-viscosity glass ionomer cement (CHC+HVGIC) or (2) restoration with HVGIC. Pulp vitality and restoration survival were evaluated at 6, 12, and 24 months. Intent-to-treat analysis was used for pulp vitality, and survival analysis was performed with the Kaplan-Meier method (α=5%). Results: At 24 months, 86 restorations were evaluated, and 91 were evaluated at least once during the study. There was no significant difference between the restorative treatments regarding pulp vitality (CHC +HVGIC=70% and HVGIC=68.5%) (OR=1.091; CI95%=0.481-2.475). However, HVGIC (73%) restorations showed a higher survival rate than CHC+HVGIC (50%) (p=0.021). Thus, it can conclude that deep caries in primary molars should be restored with HVGIC, since the technique results in similar pulp vitality to the CHC +HVGIC, but with a higher restoration survival rate.Item Treatment of infected dental pulps of monkeys with vancomycin and calcium hydroxide(1969) Gardner, Donald E.This study was undertaken to investigate histologically the effect of a combination of a potent antibiotic and calcium hydroxide when used as a medication in direct pulp therapy. The pulps of 74 teeth in one Macaca Speciosa monkey and two Macaca Nemestrina monkeys were exposed and left open to the oral environment for 48 hours to insure contamination. These pulps received direct treatment with one of four experimental medications: 1) starch and water; 2) vancomycin, starch and water; 3) calcium hydroxide, methyl cellulose and water; and 4) vancomycin, calcium hydroxide, methyl cellulose and water. In 30 days the teeth were removed from two animals and at 90 days from the other for histologic evaluation. A satisfactory response was observed in all the teeth treated with vancomycin, calcium hydroxide, methyl cellulose and water; in 94.4 per cent of the teeth treated with calcium hydroxide, methyl cellulose and water; in 33.3 per cent of those treated with vancomycin and starch; and in 11.2 per cent of those receiving starch and water. Complete bridging was seen in all teeth treated with vancomycin, calcium hydroxide, methyl cellulose and water. This was confirmed by the use of Procion brilliant red H-8BS dye and the study of serial sections. Under the conditions of this investigation, vancomycin in combination with calcium hydroxide and methyl cellulose was effective in controlling infection and promoting reparative dentin formation in monkeys.