IUPUI Research Day

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https://hdl.handle.net/1805/4255
Research Day provides an opportunity for the IUPUI faculty, staff, and students, and their academic, industrial, governmental partners, and the broader community, to come together and learn more about the research enterprise at IUPUI, explore new collaborations, and lay the foundation for new partnerships. IUPUI Research Day is sponsored by the IUPUI Office of the Vice Chancellor for Research.

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    Strategic Grantmaking in Higher Education
    (Office of the Vice Chancellor for Research, 2010-04-09) Osili, Una; Miller, Melanie; Kramarek, Michal
    Resources are scarce relative to the colossal task of tackling the barriers to higher education. Delineating a grantmaking program- given the social, political, and economic dynamics in higher education- offers a substantial challenge to the nonprofit sector. The choice of strategy, implementation, and measurement are paramount considerations in effective grantmaking. Such choices include the grantmaker’s role in community and geographical contexts, allocation of grants according to location and size, engagement in partnerships and networks, and goal setting and measurement. This study investigates best practices in strategic grantmaking in the field of higher education. Through analysis of a literature review and case study interviews, this study identifies effective strategies of grantmaking organizations in addressing barriers to higher education. Such strategies include defining organizational purpose and identity, utilization of innovative techniques, adaptation to changing systems, catalyzing research, collaboration with co-funders and grantees, “big picture” goal setting, and identification and measurement of impact. The knowledge gained from this study offers grantmakers the tools needed to heighten the impact of the organizational mission under the most effective terms.
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    Dental Health Care Service Learning Research through Volunteer Children's Programs
    (Office of the Vice Chancellor for Research, 2010-04-09) Chin, Judith; Davenport, Megan
    This volunteer program outreach service learning research was designed to expand development and participation this program and analyze reasons for participation in this program.
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    Very High Energy Electron Laser Plasma Accelerators for use in Radiotherapy
    (Office of the Vice Chancellor for Research, 2010-04-09) DesRosiers, Colleen; Moskvin, Vadim; Stewart, Keith
    Very high energy electron beams, greater than 150 MeV, have been shown to have potential benefit in radiotherapy applications. Laser plasma technology is a highly efficient electron accelerator and this technology may be used to design an optimal radiotherapy accelerator.
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    Silver Hoosiers - Health and Aging Research Lab
    (Office of the Vice Chancellor for Research, 2010-04-09) Liu, Chiung-ju
    Facing the challenge of an entire nation growing older rapidly, the mission of the Silver Hoosiers-Health and Aging Research Lab is to promote health and independence in seniors. Located in the Department of Occupational Therapy within the School of Health and Rehabilitation Sciences, this lab is led by Dr. Chiung-ju (CJ) Liu, a gerontologist, and collaborates from other schools including the School of Nursing and the School of Informatics. The poster will showcase the research conducted at the Silver Hoosiers-Health and Aging Research Lab. The lab research foci include 1) health literacy and comprehension, 2) muscle strength training and physical disability, and 3) systematic review and evidence-based practice. Dr. Liu’s health literacy work focuses on increasing accessibility of complex written health information (i.e. cancer prevention and instructions of medical devices) to seniors through the application of text cohesion and multimedia. The lab is equipped with sophisticated eye-tracking technology to study information processing load. Dr. Liu’s muscle strength training work examines the effects of progressive resistance strength training on physical functioning in older adults via meta-analysis. Additionally, Dr. Liu is in partnership with the American Occupational Therapy Association in reviewing the effects of environmental approaches on improving daily function in older adults with low vision. The aim of her review work is to provide the best research evidence to guide clinical practice. The impact of gaining is multidimensional. The lab welcomes collaborators interested in aging-related issues that share the same view of the lab’s mission.
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    Department of Music and Arts Technology's Music Therapy Program
    (Office of the Vice Chancellor for Research, 2010-04-09) Burns, Debra; Mauskapf, Phillip; Lee, Key Hwa
    The Music Therapy Program in the Department of Music and Arts Technology as two main goals: to improve the quality of life of individuals through the use of music-based interventions and to use rigorous, scientific methods to determine the best use of music-based interventions for individuals with medical and developmental needs.
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    Identification of an Actin-Based Antidiabetic Action of Chromium in Skeletal Muscle
    (Office of the Vice Chancellor for Research, 2010-04-09) Hoffman, Nolan J.; Habegger, Kirk M.; Elmendorf, Jeffrey S.
    We recently demonstrated that cortical filamentous actin (F-actin) loss contributes to cellular insulin resistance induced by hyperinsulinemia. New animal and human analyses suggest a similar loss of F-actin is present in insulin-resistant skeletal muscle and results from cellular cholesterol accrual. Interestingly, we found that chromium picolinate (CrPic), a dietary supplement recognized to improve insulin action, lowers plasma membrane cholesterol in cultured adipocytes. Understanding whether CrPic can improve F-actin structure in insulinresistant skeletal muscle via lowering membrane cholesterol is not known, yet significant, as skeletal muscle is responsible for a large majority of insulin-stimulated glucose transport. In L6 myotubes stably expressing the insulin-responsive glucose transporter GLUT4 carrying an exofacial myc-epitope tag, acute insulin stimulation (20 min, 100 nM) increased myc-epitope labeling at the surface of intact cells by ~2-fold (P<0.05). In contrast, the ability of insulin to stimulate this process was inhibited 25% (P<0.05) by sustained exposure of L6 myotubes to insulin (12 h, 5 nM). Defects in insulin signaling did not readily account for the observed disruption. However, we found that insulin-induced insulin-resistant myotubes displayed a 28% elevation (P<0.05) in membrane cholesterol with a reciprocal 14% loss (P<0.05) in F-actin. This cholesterol/actin imbalance and insulin/GLUT4 dysfunction was corrected by the cholesterollowering action of CrPic. Mechanistically, CrPic increased the activity of the AMP-activated protein kinase (AMPK). Tests also revealed that other well-recognized activators of AMPK (e.g., AICAR, DNP) lowered membrane cholesterol and that, in a fashion similar to that witnessed for CrPic, improved regulation of GLUT4 in insulin-induced insulin-resistant myotubes. These data, as well as findings from ongoing siRNA-mediated AMPK knockdown experiments, are consistent with AMPK mediating its antidiabetic action by lowering cellular cholesterol. We predict that chromium, via AMPK activation, protects against cholesterol accrual that induces skeletal muscle F-actin loss and insulin resistance.
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    Institute for American Thought
    (Office of the Vice Chancellor for Research, 2010-04-09) Pfeifer, David
    This poster will have images of recent volumes published by the critical editions being edited by the Institute for American Thought. Information will tell how long the critical editions have been in existence, how much funding has been received, and how many additional volumes will be published. The coming fifth critical edition will be mentioned. A listing of the visiting scholars for this academic year will be provided.
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    Serving the Indy Community in Multimedia
    (Office of the Vice Chancellor for Research, 2010-04-09) Huang, Edgar
    Over the years, School of Informatics faculty and students have served the community partners by creating 2D and 3D animations, shooting promotional videos, public service announcement videos, and documentary videos, design Web sites, producing games and graphic designs. This exhibit includes some examples of such works.
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    We’re All In This Together: Identifying Meaningful Outcomes for K-6 Students of Teacher Candidates
    (Office of the Vice Chancellor for Research, 2010-04-09) Fisher, Mary; Ociepka, Anne
    Connecting K-6 student outcomes with teacher preparation programs remains a critical need for the field (Bondy, 2004, Cochran-Smith, 2006). Even while we have begun to sort through and document outcomes for teacher interns relative to national standards, the task of connecting performance to K-6 student outcomes has been little documented. This interview study identified what mentor teachers associated with one urban teacher preparation program believed are positive student and associated mentor outcomes that result from student teacher participation in their elementary classrooms. This interview study consisted of an emergent analysis of individual interviews with sixteen student teacher mentors using an interview guide with a set of six questions. Data from a teacher candidate focus group which addressed a subset of these questions served to triangulate this analysis. Findings are shared in light of implications for teacher educators and their use by teacher education programs for in-depth follow-up studies. This local study, while unique to our own institution, relied on the use of a promising practice – that is, including the voice of mentor teachers – and its findings broadened the participant stakeholder base beyond the usual limited representation of university teacher educators and university researchers only.
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    Center for Urban and Multicultural Education’s Arts4Learning: Evaluation of an Early Childhood Arts Education Program
    (Office of the Vice Chancellor for Research, 2010-04-09) Smith, Joshua; Rittenhouse, Ashley; Guillot, Jerry; Pagdalian, Ploi
    CUME is a research center located in the Indiana University School of Education at Indianapolis focused on (1) Engaged Urban Teaching and Learning, (2) Community-Campus Connections/Translational Research, (3) Academic Access and Success in Urban Contexts, and (4) Urban Curriculum Research. The Arts4Learning project embodies several CUME initiatives as it infuses arts education with literacy skills and reaches out to students in both Indianapolis and Lafayette.