Browsing by Author "Yunes-Medina, Laura"

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    Immune evasion of the CD1d/NKT cell axis
    (Elsevier, 2018-06) Brutkiewicz, Randy R.; Yunes-Medina, Laura; Liu, Jianyun; Microbiology and Immunology, School of Medicine
    Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity. In contrast, here, we discuss the ways that viruses, bacteria and tumor cells can evade the CD1d/NKT cell axis. As a result, these disease states have a better chance to establish a foothold and potentially cause problems for the subsequent adaptive immune response, as the host tries to rid itself of infections or tumors.