Browsing by Author "Stephens, Jackson T. Jr"

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    Five-Year Longitudinal Assessment (2008 to 2012) of E-101 Solution Activity against Clinical Target and Antimicrobial-Resistant Pathogens
    (American Society for Microbiology (ASM), 2014-08) Denys, Gerald A.; Pillar, Chris M.; Sahm, Daniel F.; O'Hanley, Peter; Stephens, Jackson T. Jr; Department of Pathology & Laboratory Medicine, IU School of Medicine
    This study summarizes the topical E-101 solution susceptibility testing results for 760 Gram-positive and Gram-negative target pathogens collected from 75 U.S. sites between 2008 and 2012 and 103 ESKAPE pathogens. E-101 solution maintained potent activity against all bacterial species studied for each year tested, with MICs ranging from <0.008 to 0.25 μg porcine myeloperoxidase (pMPO)/ml. These results confirm that E-101 solution retains its potent broad-spectrum activity against U.S. clinical isolates and organisms with challenging resistance phenotypes.