Browsing by Author "Fineberg, Naomi"

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    Establishment of a clinically correlated human pericardial fluid bank: Evaluation of intrapericardial diagnostic potential
    (Wiley, 1999-01) Dickson, Tonya J.; Nguyen, A.Q.; Kumfer, K.; Maxted, W.; Gurudutt, Vivek; Brown, John; Mahomed, Yousuf; Sharp, Thomas; Aufiero, Thomas X.; Fineberg, Naomi; March, Keith L.; Medicine, School of Medicine
    The development of a clinically correlated human pericardial fluid bank and database is described. A unique feature of this registry is the availability of a large number of pericardial fluid samples for testing with respect to multiple factors and for correlation with angiographic findings and clinical syndromes expressed by the patients. The collection of data at the present time comprises frozen pericardial fluid samples obtained from patients who have undergone cardiac surgery; and historical, clinical, and laboratory data obtained from the patient records. Nearly 400 samples have been stored and analyzed thus far, with sample entry continuing. This registry is designed to evaluate the local factors that play a role in mediating or reflecting myocardial or coronary responses. Pathophysiologic processes of particular interest include restenosis, plaque ruptures, and angiogenesis. Study of the pericardial fluid bank should lead to enhanced understanding of molecular mechanisms, as well as to the explanation for the reasons underlying interpatient variability in these processes. It is further anticipated that this information might provide a foundation for the diagnostic use of pericardial fluid to individualize therapies targeting angiogenesis or plaque physiology.
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    Nutrition Management of Type 2 Diabetes by Primary Care Physicians
    (2000-11) Marrero, David G.; Kraft, Stephanie Kakos; Mayfield, Jennifer; Wheeler, Madelyn L.; Fineberg, Naomi
    A survey was mailed to a probability sample of primary care physicians in Indiana to assess their use of and barriers to nutritional therapy for patients with type 2 diabetes. Most (62%) primary care physicians reported referring their type 2 diabetes patients for nutrition counseling, while 38% reported providing counseling themselves. Patient-centered barriers were most frequently cited as reasons for poor effectiveness of nutrition therapy. This differs from previous research that cites system-level factors as barriers.
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    A Spatial Analysis of Obesogenic Environments for Children
    (2002) Liu, Gilbert C.; Cunningham, Cynthia; Downs, Stephen M.; Marrero, David G.; Fineberg, Naomi
    In this study, we use spatial analysis techniques to explore environmental and social predictors of obesity in children. We constructed a merged database, incorporating clinical data from an electronic medical record system, the Regenstrief Medical Record System (RMRS) and societal & environmental data from a geographical information system, the Social Assets and Vulnerabilities Indicators (SAVI) Project. We used the RMRS to identify cohorts of children that were normal weight, overweight, or obese. The RMRS records were geocoded and merged into the SAVI database. Using the merged databases, we analyzed the relationships between markers of socioeconomic status and obesity outcomes in children. Our preliminary analyses show that markers of low socioeconomic status at the census tract level correlate with both overweight and obese outcomes in our study population. Utilization of geographic information systems (GIS) for the study of health epidemiology is discussed.