Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element.
| dc.contributor.author | Leroy, P | |
| dc.contributor.author | Nakshatri, H | |
| dc.contributor.author | Chambon, P | |
| dc.date.accessioned | 2019-04-17T21:16:56Z | |
| dc.date.available | 2019-04-17T21:16:56Z | |
| dc.date.issued | 1991-11-15 | |
| dc.description.abstract | We have characterized the promoter of the mouse retinoic acid receptor alpha 2 (mRAR-alpha 2) isoform. This promoter contains a retinoic acid response element (RARE) that closely resembles the RARE that is present in the RAR-beta 2 promoter. Moreover, RAR-alpha 2 and RAR-beta 2 proximal promoter sequences are similar to each other and generate transcripts whose respective start sites are located at similar positions. The RAR-alpha 2 RARE consists of two directly repeated 5'-GTTCA-3' motifs to which all three RARs (alpha, beta, and gamma) bind in vitro. | en_US |
| dc.identifier.citation | Leroy, P., Nakshatri, H., & Chambon, P. (1991). Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element. Proceedings of the National Academy of Sciences of the United States of America, 88(22), 10138–10142. | en_US |
| dc.identifier.issn | 0027-8424 | |
| dc.identifier.uri | https://hdl.handle.net/1805/18882 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | National Academy of Sciences | en_US |
| dc.subject | mouse retinoic acid | en_US |
| dc.subject | isoform | en_US |
| dc.subject | nuclear receptor genes | en_US |
| dc.title | Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element. | en_US |
| dc.type | Article | en_US |