Therapeutic Options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – possible lessons from a systematic review of SARS-CoV therapy

dc.contributor.authorMomattin, Hisham
dc.contributor.authorMohammed, Khurram
dc.contributor.authorZumla, Alimuddin
dc.contributor.authorMemish, Ziad A.
dc.contributor.authorAl-Tawfiq, Jaffar A.
dc.contributor.departmentDepartment of Medicine, Indiana University School of Medicineen_US
dc.date.accessioned2020-06-10T18:28:17Z
dc.date.available2020-06-10T18:28:17Z
dc.date.issued2013-08-29
dc.descriptionThis article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
dc.description.abstractThe Middle East Respiratory Syndrome coronavirus (MERS-CoV) has been detected in a number of countries in the Middle East and Europe with an apparently high mortality rate. It is phylogenetically related to the SARS coronavirus and has also been associated with severe respiratory illness as well as nosocomial transmission in healthcare settings. Current international recommendations do not support any specific therapies; however, there are a number of agents, which were used during the SARS epidemic of 2003. It is possible that these might be active against the related MERS coronavirus. We have reviewed the literature on the safety and efficacy of therapies used in patients with SARS with a view to their potential use in patients with MERS-CoV infections.en_US
dc.eprint.versionFinal published versionen_US
dc.identifier.citationMomattin, H., Mohammed, K., Zumla, A., Memish, Z. A., & Al-Tawfiq, J. A. (2013). Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)--possible lessons from a systematic review of SARS-CoV therapy. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 17(10), e792–e798. https://doi.org/10.1016/j.ijid.2013.07.002en_US
dc.identifier.urihttps://hdl.handle.net/1805/22932
dc.language.isoen_USen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.ijid.2013.07.002en_US
dc.relation.journalInternational Journal of Infectious Diseasesen_US
dc.rightsPublisher Policy*
dc.rightsThis article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
dc.sourcePMCen_US
dc.subjectMERS-CoVen_US
dc.subjectInterferonen_US
dc.subjectRibavarinen_US
dc.subjectSARSen_US
dc.titleTherapeutic Options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) – possible lessons from a systematic review of SARS-CoV therapyen_US
dc.typeArticleen_US
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