A review of factors affecting the success of membrane protein crystallization using bicelles

dc.contributor.author	Kimble-Hill, Ann C.
dc.date.accessioned	2014-09-19T18:29:41Z
dc.date.available	2014-09-19T18:29:41Z
dc.date.issued	2013-06
dc.description	Author's manuscript made available in accordance with the publisher's policy.	en_US
dc.description.abstract	Several reports have been published detailing various platforms for obtaining crystals of membrane proteins to determine their structure including those that use disk shaped bilayers called bicelles. While these crystals have been readily grown and used for x-ray diffraction, the general understanding as to why bicelles are adequate for such a procedure or how to rationally choose conditions remains unknown. This review intends to discuss issues of protein stabilization and precipitation in the presence of lipids that may influence crystal formation.	en_US
dc.identifier.citation	Kimble-Hill AC. A review of factors affecting the success of membrane protein crystallization using bicelles. Front Biol. 2013 Jun 1;8(3):261–72.	en_US
dc.identifier.uri	https://hdl.handle.net/1805/5071
dc.language.iso	en_US	en_US
dc.publisher	Frontiers in Biology (Higher Education Press and Springer-Verlag)	en_US
dc.subject	Biochemistry	en_US
dc.subject	bicelle	en_US
dc.subject	membrane protein	en_US
dc.subject	crystallization	en_US
dc.title	A review of factors affecting the success of membrane protein crystallization using bicelles	en_US
dc.type	Article	en_US

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