Browsing by Subject "virus"

Now showing 1 - 3 of 3
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    Ebola Virus Disease - Legal and Ethical Considerations for Indiana
    (Richard M. Fairbanks School of Public Health, 2014-10) Williams, Matthew; Silverman, Ross; Duwve, Joan
    The Ebola Virus Disease (EVD), formally known as Ebola hemorrhagic fever, is a virulent and often deadly infectious disease. Fatality rates for the disease have reported to be as high as 90% following contraction. As of October 14, 2014, a total of 8,914 probable, confirmed, and suspected cases of EVD and 4,447 deaths due to the disease, have been reported to the World Health Organization (WHO) by the nations of Liberia, Guinea, and Sierra Leon.
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    Hepatitis B Virus X Protein Crosses Out Smc5/6 Complex to Maintain cccDNA Transcription
    (Wiley, 2016-12) Mitra, Bidisha; Guo, Haitao; Microbiology and Immunology, School of Medicine
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    Molecular Typing of Canine Parvovirus from Sulaimani, Iraq and Phylogenetic Analysis Using Partial Vp2 Gene
    (Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria, 2017-09) Sheikh, M. O. Baba; Rashid, P. M. A.; Marouf, A. S.; Raheem, Z. H.; Manjunath, S.; Janga, Sarath Chandra; Medical and Molecular Genetics, School of Medicine
    Canine parvovirus (CPV) remains the most significant viral cause of haemorrhagic enteritis and bloody diarrhoea in puppies over the age of 12 weeks. The objective of the present study was to detect and genotype CPV-2 by polymerase chain reaction (PCR) and to perform phylogenetic analysis using partial VP2 gene sequences. We analysed eight faecal samples of unvaccinated dogs with signs of vomiting and bloody diarrhoea during the period from December 2013 to May 2014 in different locations in Sulaimani, Kurdistan, Iraq. After PCR detection, we found that all viral sequences in our study were CPV-2b variants, which differed genetically by 0.8% to 3.6% from five commercially available vaccines. Alignment between eight nucleotides of field virus sequences showed 95% to 99.5% similarity. The phylogenetic analysis for the 8 field sequences formed two distinct clusters with two sequences belonging to strains from China and Thailand and the other six - with a strain from Egypt. Molecular characterisation and CPV typing are crucial in epidemiological studies for future prevention and control of the disease.