Browsing by Subject "ventilation"

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    Overcoming Barriers to Efficiency
    (2005-09) Lawrence, Thomas M.; Mullen, Jeffrey D.; Noonan, Douglas S.; Enck, Jay
    The article discusses factors that hinder the installation of high-performance heating, ventilation and air conditioning (HVAC) equipment in commercial and residential buildings in the United States. For owner-occupied buildings, the utility and capital expenses are ultimately included in one corporate budget. Thus, decision processes become a justification of any additional expense for higher performing equipment relative to the expected returns via lower energy costs. In an existing building, business management principles determine the evaluation process. Certain economic factors apply regardless of building ownership. For example, a cost is associated with the information gathering process for new technology or obtaining information relevant to current resource use. This is primarily a direct expense in the form of employee salaries or consultant fees. INSET: Sustainable HVAC for Modular Classrooms.
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    Ventilation Strategies during Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure: Current Approaches among Level IV Neonatal ICUs
    (Wolters Kluwer, 2022-11) Ibrahim, John; Mahmood, Burhan; DiGeronimo, Robert; Rintoul, Natalie E.; Hamrick, Shannon E.; Chapman, Rachel; Keene, Sarah; Seabrook, Ruth B.; Billimoria, Zeenia; Rao, Rakesh; Daniel, John; Cleary, John; Sullivan, Kevin; Gray, Brian; Weems, Mark; Dirnberger, Daniel R.; Surgery, School of Medicine
    OBJECTIVES: To describe ventilation strategies used during extracorporeal membrane oxygenation (ECMO) for neonatal respiratory failure among level IV neonatal ICUs (NICUs). DESIGN: Cross-sectional electronic survey. SETTING: Email-based Research Electronic Data Capture survey. PATIENTS: Neonates undergoing ECMO for respiratory failure at level IV NICUs. INTERVENTIONS: A 40-question survey was sent to site sponsors of regional referral neonatal ECMO centers participating in the Children’s Hospitals Neonatal Consortium. Reminder emails were sent at 2- and 4-week intervals. MEASUREMENTS AND MAIN RESULTS: Twenty ECMO centers responded to the survey. Most primarily use venoarterial ECMO (65%); this percentage is higher (90%) for congenital diaphragmatic hernia. Sixty-five percent reported following protocol-based guidelines, with neonatologists primarily responsible for ventilator management (80%). The primary mode of ventilation was pressure control (90%), with synchronized intermittent mechanical ventilation (SIMV) comprising 80%. Common settings included peak inspiratory pressure (PIP) of 16–20 cm H2O (55%), positive end-expiratory pressure (PEEP) of 9–10 cm H2O (40%), I-time 0.5 seconds (55%), rate of 10–15 (60%), and Fio2 22–30% (65%). A minority of sites use high-frequency ventilation (HFV) as the primary mode (5%). During ECMO, 55% of sites target some degree of lung aeration to avoid complete atelectasis. Fifty-five percent discontinue inhaled nitric oxide (iNO) during ECMO, while 60% use iNO when trialing off ECMO. Nonventilator practices to facilitate decannulation include bronchoscopy (50%), exogenous surfactant (25%), and noninhaled pulmonary vasodilators (50%). Common ventilator thresholds for decannulation include PEEP of 6–7 (45%), PIP of 21–25 (55%), and tidal volume 5–5.9 mL/kg (50%). CONCLUSIONS: The majority of level IV NICUs follow internal protocols for ventilator management during neonatal respiratory ECMO, and neonatologists primarily direct management in the NICU. While most centers use pressure-controlled SIMV, there is considerable variability in the range of settings used, with few centers using HFV primarily. Future studies should focus on identifying respiratory management practices that improve outcomes for neonatal ECMO patients.