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Item How Can We Optimize Tools and Techniques for Endoscopic Ultrasound–Guided Liver Biopsy?(Elsevier, 2020-05) Obaitan, Itegbemie; Al-Haddad, Mohammad A.; Medicine, School of MedicineItem MutDB: update on development of tools for the biochemical analysis of genetic variation(Oxford University Press, 2007-09-07) Singh, Arti; Olowoyeye, Adebayo; Baenziger, Peter H.; Dantzer, Jessica; Kann, Maricel G.; Radivojac, Predrag; Heiland, Randy; Mooney, Sean D.; Medical and Molecular Genetics, School of MedicineUnderstanding how genetic variation affects the molecular function of gene products is an emergent area of bioinformatic research. Here, we present updates to MutDB ( http://www.mutdb.org ), a tool aiming to aid bioinformatic studies by integrating publicly available databases of human genetic variation with molecular features and clinical phenotype data. MutDB, first developed in 2002, integrates annotated SNPs in dbSNP and amino acid substitutions in Swiss-Prot with protein structural information, links to scores that predict functional disruption and other useful annotations. Though these functional annotations are mainly focused on nonsynonymous SNPs, some information on other SNP types included in dbSNP is also provided. Additionally, we have developed a new functionality that facilitates KEGG pathway visualization of genes containing SNPs and a SNP query tool for visualizing and exporting sets of SNPs that share selected features based on certain filters.Item Technical Communication and Project Management: A Mixed Methods Study in a Corporate Context(IEEE, 2018-07) Miller, Rosemarie T.; Hovde, Marjorie Rush; Technology and Leadership Communication, School of Engineering and TechnologyA mid-size manufacturing business grew from a family start-up to a global leader in less than three decades, but no plan was developed for Project Management or Technical Communication. Recently upper management acknowledged this corporate weakness and asked us to research interdepartmental communication, with emphasis on New Product Development. Formal Project Management had not previously been attempted at this company, and New Product Development was conducted as a committee. After a literature review, we conducted a mixed-method study to assess employee satisfaction with current project processes, technology, and communication. A survey combining two existing tools was administered to all personnel in departments involved with New Product Development. Downs and Hazen's Communication Satisfaction Questionnaire was tailored to evaluate the company's communications, and a customized version of the Universal Technology Adoption and Use Theory tool assessed technology use and acceptance within the company. Subsequent to the survey, all department managers directly involved with New Product Development at the organization were interviewed. Quantitative results were analyzed statistically, and qualitative results were analyzed through open coding. Findings from this study can provide insight into the dynamics of improving both Project Management and Technical Communication within a corporate context.