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Item COVID-19 Infection versus Influenza (Flu) and Other Respiratory Illnesses(ATS, 2020-11) Sockrider, Marianna; Jamil, Shazia; Santhosh, Lekshmi; Carlos, W. Graham; Medicine, School of MedicineSARS-CoV-2 is the virus that causes the COVID-19 infection. You can be ill with more than one virus at the same time. As the SARS-CoV-2 virus pandemic continues, influenza and other respiratory infections will also emerge in the community. Respiratory infections may present with similar symptoms and all can spread from person to person. It is hard to tell which virus or bacteria is causing a person’s illness based on symptoms alone. At times testing is needed to see which virus(es) or bacteria are present. These tests usually involve getting a nose and/or throat swab sample, as most of these viruses are present in large amounts in the back of the nose and throat. There is still a lot to learn about the COVID-19 infection and research is ongoing.Item Household-level risk factors for secondary influenza-like illness in a rural area of Bangladesh(Wiley, 2020) Weaver, Anne M.; Khatun-e-Jannat, Kaniz; Cercone, Emily; Krytus, Kimberly; Sohel, Badrul Munir; Ahmed, Makhdum; Rahman, Mustafizur; Azziz-Baumgartner, Eduardo; Yu, Jihnhee; Fry, Alicia M.; Luby, Stephen P.; Ram, Pavani K.; Global Health, School of Public HealthObjective To describe household‐level risk factors for secondary influenza‐like illness (ILI), an important public health concern in the low‐income population of Bangladesh. Methods Secondary analysis of control participants in a randomised controlled trial evaluating the effect of handwashing to prevent household ILI transmission. We recruited index‐case patients with ILI – fever (<5 years); fever, cough or sore throat (≥5 years) – from health facilities, collected information on household factors and conducted syndromic surveillance among household contacts for 10 days after resolution of index‐case patients’ symptoms. We evaluated the associations between household factors at baseline and secondary ILI among household contacts using negative binomial regression, accounting for clustering by household. Results Our sample was 1491 household contacts of 184 index‐case patients. Seventy‐one percentage reported that smoking occurred in their home, 27% shared a latrine with one other household and 36% shared a latrine with >1 other household. A total of 114 household contacts (7.6%) had symptoms of ILI during follow‐up. Smoking in the home (RRadj 1.9, 95% CI: 1.2, 3.0) and sharing a latrine with one household (RRadj 2.1, 95% CI: 1.2, 3.6) or >1 household (RRadj 3.1, 95% CI: 1.8–5.2) were independently associated with increased risk of secondary ILI. Conclusion Tobacco use in homes could increase respiratory illness in Bangladesh. The mechanism between use of shared latrines and household ILI transmission is not clear. It is possible that respiratory pathogens could be transmitted through faecal contact or contaminated fomites in shared latrines.