Browsing by Subject "recurrence rate"

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    Recurrence rates after EMR of large sessile serrated polyps
    (Elsevier, 2015-09) Rex, Kevin D.; Vemulapalli, Krishna C.; Rex, Douglas K.; Department of Medicine, School of Medicine
    Background Little is known regarding the recurrence rate after EMR of large (≥20 mm) sessile serrated adenoma/polyps (SSA/Ps). Objective To compare the recurrence rate among SSA/Ps and conventional adenomas in patients referred to a specialty practice for EMR. Design Retrospective cohort study. Setting Academic hospital and a satellite surgery center. Patients A total of 362 consecutive patients referred for resection of large (≥20 mm) polyps in the colorectum. Interventions All EMRs were performed with a submucosal contrast agent. All subjects had a follow-up surveillance examination (inspection and biopsy of the EMR) at our center. Main Outcome Measurements Rates of residual polyp at follow-up examination. Results Residual polyp was identified among 8.7% of SSA/Ps compared with 11.1% for conventional adenomas (P = .8). Limitations Retrospective design, procedures performed by a single experienced endoscopist, low number of serrated lesions. Conclusions The rate of recurrence after EMR of SSA/Ps is similar to the rate after EMR of conventional adenomas.
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    Reduction in overt and silent stroke recurrence rate following cerebral revascularization surgery in children with sickle cell disease and severe cerebral vasculopathy
    (Wiley, 2016-08) Hall, Erin M.; Leonard, Jeffrey; Smith, Jodi L.; Guilliams, Kristin P.; Binkley, Michael; Fallon, Robert J.; Hulbert, Monica L.; Neurological Surgery, School of Medicine
    Background Children with sickle cell disease (SCD) and moyamoya may benefit from indirect cerebral revascularization surgery in addition to chronic blood transfusion therapy for infarct prevention. We sought to compare overt and silent infarct recurrence rates in children with SCD undergoing revascularization. Methods This was a retrospective cohort study of all children with SCD and moyamoya treated at two children’s hospitals. Clinical events and imaging studies were reviewed. Results Twenty-seven children with SCD and confirmed moyamoya receiving chronic transfusion therapy were identified, of whom 12 underwent indirect cerebral revascularization. Two subjects had post-operative transient ischemic attacks and another had a subarachnoid blood collection, none of which caused permanent consequences. Two subjects had surgical wound infections. Among these 12 children, the rate of overt and silent infarct recurrence decreased from 13.4 infarcts/100 patient-years before revascularization to 0 infarcts/100 patient-years after revascularization (p=0.0057); the post-revascularization infarct recurrence rate was also significantly lower than the overall infarct recurrence of 8.87 infarcts/100 patient-years in 15 children without cerebral revascularization (p=0.025). Conclusion The rate of overt and silent infarct recurrence was significantly lower following indirect cerebral revascularization. A prospective study of cerebral revascularization in children with SCD is needed.